DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT7 and Cct7

DIOPT Version :9

Sequence 1:	NP_649835.1	Gene:	CCT7 / 41054	FlyBaseID:	FBgn0037632	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_031664.3	Gene:	Cct7 / 12468	MGIID:	107184	Length:	544	Species:	Mus musculus

Alignment Length:	539	Identity:	406/539 - (75%)
Similarity:	470/539 - (87%)	Gaps:	1/539 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQPQIVLLKEGTDSSQGKPQLVSNINACQSIVDAVRTTLGPRGMDKLIVDAHGKATISNDGATIM 65
            |...::|||||||||||.|||||||:|||.|.:|||||||||||||||||..||||||||||||:
Mouse     2 MPTPVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATIL 66

  Fly    66 KLLEIIHPAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQL 130
            |||:::|||||||||||||||||||||||||.|||.||||||||:||||:||::||:|.|.|.||
Mouse    67 KLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQL 131

  Fly   131 CMEKINEMAVQIVEQSKDQQRALLEKCAATAMSSKLIHQQKDFFSRIVVDAVLSLDELLPLNMIG 195
            .:.||.|:||.:.:|.|.:||.:|||||.||:|||||.|||.||:::|||||:.|||||.|.|||
Mouse   132 AVNKIKEIAVTVKKQDKVEQRKMLEKCAMTALSSKLISQQKVFFAKMVVDAVMMLDELLQLKMIG 196

  Fly   196 IKKVTGGSLEESQLVSGVAFKKTFSYAGFEMAPKSYDNCKIALLNIELELKAERDNAEIRVDNVK 260
            ||||.||:|||||||:|||||||||||||||.||.|.|.||||||:|||||||:|||||||..|:
Mouse   197 IKKVQGGALEESQLVAGVAFKKTFSYAGFEMQPKKYKNPKIALLNVELELKAEKDNAEIRVHTVE 261

  Fly   261 EYQKVVDAEWQILYNKLAKIHESGANVVLSKLPIGDVATQYFADRDIFCAGRVPEEDLKRTMKAC 325
            :||.:|||||.|||:||.|||:|||.|:||||||||||||||||||:|||||||||||||||.||
Mouse   262 DYQAIVDAEWNILYDKLEKIHQSGAKVILSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMAC 326

  Fly   326 GGAVMTTANDIKPNVLGLCEHFEERQVGGERFNLFQGCPNAKTSTLILRGGAEQFLEETERSLHD 390
            ||::.|:.|.:.|:|||.|:.|||.|:||||:|.|.|||.|||.|:|||||||||:|||||||||
Mouse   327 GGSIQTSVNALVPDVLGHCQVFEETQIGGERYNFFTGCPKAKTCTIILRGGAEQFMEETERSLHD 391

  Fly   391 AIMIVRRTIKHDSVVAGGGAIEMELSKLLRDYSRTIAGKEQLLIAAIAKGLEIIPRQLCDNAGFD 455
            |||||||.||:||||||||||||||||.||||||||.||:||||.|.||.|||||||||||||||
Mouse   392 AIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFD 456

  Fly   456 ATNILNKLRQKHAQGGQWYGVDINKEDISDNYEQCVWEPSIIKINALTAAAEAACMILSVDETIK 520
            |||||||||.:|||||.|||||||.|:|:||::..||||::::|||||||:||||:|:|||||||
Mouse   457 ATNILNKLRARHAQGGMWYGVDINNENIADNFQAFVWEPAMVRINALTAASEAACLIVSVDETIK 521

  Fly   521 SPKAG-EPPMAGGGMGMGR 538
            :|::. :||....|.|.|:
Mouse   522 NPRSTVDPPAPSAGRGRGQ 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT7	NP_649835.1	chap_CCT_eta	2..524	CDD:274086	400/521 (77%)
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	400/519 (77%)
Cct7	NP_031664.3	chap_CCT_eta	3..525	CDD:274086	400/521 (77%)
		TCP1_eta	5..525	CDD:239456	400/519 (77%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	523..544		6/18 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839910
Domainoid	1	1.000	763	1.000	Domainoid score	I82
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4694
Inparanoid	1	1.050	816	1.000	Inparanoid score	I473
Isobase	1	0.950	-	0	Normalized mean entropy	S7
OMA	1	1.010	-	-		QHG60896
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004859
OrthoInspector	1	1.000	-	-		oto95177
orthoMCL	1	0.900	-	-		OOG6_101782
Panther	1	1.100	-	-	LDO	PTHR11353
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1489
SonicParanoid	1	1.000	-	-		X3429
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740