Protein Alignment CCT7 and CCT6B

DIOPT Version :10

• Sequence 1: NP_649835.1
• Gene: CCT7 / 41054
• FlyBaseID: FBgn0037632
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_006575.2
• Gene: CCT6B / 10693
• HGNCID: 1621
• Length: 530
• Species: Homo sapiens
• Alignment Length: 522
• Identity: 142/522 - (27%)
• Similarity: 261/522 - (50%)
• Gaps: 26/522 - (4%)

  Fly    15 SQGKPQLVSNINACQSIVDAVRTTLGPRGMDKLIVDAHGKATISNDGATIMKLLEIIHPAAKTLV 79
            ::.:..|..||.|.:.:.|.:||.|||:|..|::|...|...::.||..::..::|.||.|..:.
Human    14 ARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHPTASLIA 78

  Fly    80 DIAKSQDAEVGDGTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQLCMEKINEMAVQIVE 144
            .:|.:||...||||||.||:.||.|||...::.||:|||:|.:....|....:|.:.|:.|
Human    79 KVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEEVKV---- 139

  Fly   145 QSKDQQRALLEKCAATAMSSKLIHQQKDFFSRIVVDAVLSLD------ELLPLNMIGIKKVTGGS 203
             :|:.:|.:|...|.|::.:|:..:..|..:.:|||:||::.      :|..:.::.:|...|
Human   140 -TKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVRRPGYPIDLFMVEIMEMKHKLG-- 201

  Fly   204 LEESQLVSGVAFKKTFSYAGFEMAPKSYDNCKIALLNIELELKAERDNAEIRVDNVKEYQKVVDA 268
             .:::|:.|:.......:...:   |..::..|.:.|:.||.:....|:.......:|.:|:|.|
Human   202 -TDTKLIQGLVLDHGARHPDMK---KRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEKLVKA 262

  Fly   269 EWQILYNKLAKI---------HESGANVVLSKLPIGDVATQYFADRDIFCAGRVPEEDLKRTMKA 324
            |.:.:.:::.||         ..:...||:::..|...:....|...|....|....:::|...|
Human   263 ERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLA 327

  Fly   325 CGGAVMTTANDIKPNVLGLCEHFEERQVGGERFNLFQGCPNAKTSTLILRGGAEQFLEETERSLH 389
            |||..:.:..|:..:.||......|..:|.|:|...:.|.|..:.||:::|..:..|.:.:.::.
Human   328 CGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIR 392

  Fly   390 DAIMIVRRTIKHDSVVAGGGAIEMELSKLLRDYSRTIAGKEQLLIAAIAKGLEIIPRQLCDNAGF 454
            |.:..::..|:...:|.|.||||:.:::.|..|..:|.|:.:|.:.|.|..|.|||:.|..|||:
Human   393 DGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGY 457

  Fly   455 DATNILNKLRQKHAQGGQWYGVDINKEDISDNYEQCVWEPSIIKINALTAAAEAACMILSVDETI 519
            |....|.|::.:|.:..|..|||:|..:.....:..||:...:|...|.:....|..||.|||.:
Human   458 DPQETLVKVQAEHVESKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIM 522

  Fly   520 KS 521
            ::
Human   523 RA 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	142/522 (27%)
CCT6B	NP_006575.2	chap_CCT_zeta	3..530	CDD:274088	142/522 (27%)