Protein Alignment CCT7 and CCT4

DIOPT Version :9

• Sequence 1: NP_649835.1
• Gene: CCT7 / 41054
• FlyBaseID: FBgn0037632
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_006421.2
• Gene: CCT4 / 10575
• HGNCID: 1617
• Length: 539
• Species: Homo sapiens
• Alignment Length: 527
• Identity: 179/527 - (33%)
• Similarity: 305/527 - (57%)
• Gaps: 24/527 - (4%)

  Fly    10 EGTDSSQGKPQLV--SNINACQSIVDAVRTTLGPRGMDKLIVDAHGKATISNDGATIMKLLEIIH 72
            :|....:.||..:  |||:|.:::.||:||:|||:||||:|.|..|..||:||||||:|.::::|
Human    21 KGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLH 85

  Fly    73 PAAKTLVDIAKSQDAEVGDGTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQLCMEKINE 137
            |||:.||:::|:||.|.||||||||::||..|......:::|:||.:|.::.:|||:..:|.:.:
Human    86 PAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILTD 150

  Fly   138 MAVQIVEQSKDQQRALLEKCAATAMSSKLIHQQKDFFSRIVVDAVLSLDE-----LLPLNMIGIK 197
            |: :.||.|   .|..|...|.|:::||::.|.....|.:.|:||:.:.:     .:.|..|.|.
Human   151 MS-RPVELS---DRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIV 211

  Fly   198 KVTGGSLEESQLVSGVAFKKTFSYAGFEMAPKSYDNCKIALLNIELEL-KAERDNAEIRVDNVKE 261
            |..||::::.:||.|:...:..|.:|.....|:    ||.|:...|.. |.:.|| :|.|.:..:
Human   212 KKLGGTIDDCELVEGLVLTQKVSNSGITRVEKA----KIGLIQFCLSAPKTDMDN-QIVVSDYAQ 271

  Fly   262 YQKVVDAEWQILYNKLAKIHESGANVVLSKLPI-----GDVATQYFADRDIFCAGRVPEEDLKRT 321
            ..:|:..|...:.|.:.:|.::|.||:|.:..|     .|:|..:.....|.....:..||::..
Human   272 MDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFI 336

  Fly   322 MKACGGAVMTTANDIKPNVLGLCEHFEERQVGGE-RFNLFQGCPN-AKTSTLILRGGAEQFLEET 384
            .|..|...:...:....::||..|..||..:.|. :.....||.: .||.|:::||..:..:||.
Human   337 CKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPGKTVTIVVRGSNKLVIEEA 401

  Fly   385 ERSLHDAIMIVRRTIKHDSVVAGGGAIEMELSKLLRDYSRTIAGKEQLLIAAIAKGLEIIPRQLC 449
            |||:|||:.::|..:|..:::|||||.|:||:..|.:||||::|.|...:.|.|..:|:||..|.
Human   402 ERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLA 466

  Fly   450 DNAGFDATNILNKLRQKHAQGGQWYGVDINKEDISDNYEQCVWEPSIIKINALTAAAEAACMILS 514
            :|||.:..:.:.:||.:||||.:..|:::.|..||:..|:.|.:|.::.::|||.|.|....||.
Human   467 ENAGLNPISTVTELRNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILK 531

  Fly   515 VDETIKS 521
            :|:.:.:
Human   532 IDDVVNT 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT7	NP_649835.1	chap_CCT_eta	2..524	CDD:274086	179/527 (34%)
		TCP1_eta	4..524	CDD:239456	179/527 (34%)
CCT4	NP_006421.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		1/7 (14%)
		TCP1_delta	25..538	CDD:239454	178/521 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60896
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820