DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCT7 and hspd1

DIOPT Version :9

Sequence 1:	NP_649835.1	Gene:	CCT7 / 41054	FlyBaseID:	FBgn0037632	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_001096355.1	Gene:	hspd1 / 100124945	XenbaseID:	XB-GENE-980059	Length:	576	Species:	Xenopus tropicalis

Alignment Length:	569	Identity:	131/569 - (23%)
Similarity:	233/569 - (40%)	Gaps:	95/569 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 IVDAVRTTLGPRGMDKLIVDAHGKATISNDGATIMKLLEI----IHPAAKTLVDIAKSQDAEVGD 91
            :.|||..|:||:|...:|..:.|...::.||.|:.|.:::    .:..||.:.|:|.:.:.|.||
Frog    47 LADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKAIDLKDKYKNIGAKLVQDVANNTNEEAGD 111

  Fly    92 GTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQLCMEKINEMAVQIVEQSKDQQRALL-- 154
            |||:..:||....|:....:.:|.:|    ..||:.:.:.::       .::::.|:|.:.:.
Frog   112 GTTTATVLARSIAKEGFEKISKGANP----VEIRRGVMMAVD-------AVIKELKNQSKPVTTP 165

  Fly   155 EKCAATAMSSKLIHQQKDFFSRIVVDAVLSLDELLPLNMIGIKKVTGGSL--EESQLVSGVAFKK 217
            |:.|..|..|....|:   ..:|:.||:..:...      |:..|..|..  :|.:::.|:.|.:
Frog   166 EEIAQVATISANGDQE---IGKIISDAMKRVGRR------GVITVKDGKTLHDELEIIEGMKFDR 221

  Fly   218 TFSYAGFEMAPKSYDNCKIA---LLNIELELKAERDNA-EIRVDNVKEYQKVVDAE-------WQ 271
            .:....|....|. ..|:..   ||..|.::.:.:... .:.:.|......|:.||       ..
Frog   222 GYISPYFINTAKG-QKCEFQDAYLLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALST 285

  Fly   272 ILYNKLAKIHESGANVVLSKLP-IGDVATQYFADRDIFCAGRV-PEEDLKRTMKACG-------G 327
            ::.|:|    :.|..||..|.| .||.......|..|...|.| .||.|...::...       |
Frog   286 LVLNRL----KVGLQVVAVKAPGFGDNRKNQLKDMAISSGGVVFGEEGLTLNIEDIQPHDFGKVG 346

  Fly   328 AVMTTAND------------IKPNVLGLCEHFEERQVGGERFNLFQGCPNAKTSTLILRGGAEQF 380
            .|:.|.:|            |:..:..:.|..|......|:..|.:..........:::.|....
Frog   347 EVIVTKDDTMLLKGKGDKAQIEKRIQEIHEQLESTNSEYEKEKLNERLAKLSDGVAVIKVGGTSD 411

  Fly   381 LEETERS--LHDAIMIVRRTIKHDSVVAGGGAIEMELSKLLRDYSRTIAGKEQLLIAAIAKGLEI 443
            :|..|:.  :.||:...|..:: :.:|.|||...:.....|.  :...|.::|.:      |:||
Frog   412 VEVNEKKDRVTDALNATRAAVE-EGIVLGGGCALLRCIPALE--ALNPANEDQRV------GIEI 467

  Fly   444 IPRQL-------CDNAGFDATNILNKLRQKHAQGGQWYGVDINKEDISDNYEQCVWEPSIIKINA 501
            |.|.|       ..|||.:.:.::.|:.|...:    .|.|....:..:..|:.:.:|:.:...|
Frog   468 IRRTLKIPAMTIAKNAGVEGSLVVEKIIQSPVE----IGYDAMHAEFVNLVEKGIIDPTKVVRTA 528

  Fly   502 LTAAAEAACMILS----VDETIKSPKAGEPPMAG-GGM-GMGRGMGRPM 544
            |..||..|.::.:    |.|..|..|.|  .||| ||| ||..|||..|
Frog   529 LMDAAGVASLLTTAEAVVTEIPKEEKDG--GMAGMGGMGGMPGGMGGGM 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT7	NP_649835.1	chap_CCT_eta	2..524	CDD:274086	117/545 (21%)
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	117/545 (21%)
hspd1	NP_001096355.1	GroEL	28..548	CDD:239460	115/538 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910