DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCT7 and bbs10

DIOPT Version :9

Sequence 1:	NP_649835.1	Gene:	CCT7 / 41054	FlyBaseID:	FBgn0037632	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	XP_021323237.1	Gene:	bbs10 / 100034535	ZFINID:	ZDB-GENE-060503-355	Length:	567	Species:	Danio rerio

Alignment Length:	519	Identity:	102/519 - (19%)
Similarity:	173/519 - (33%)	Gaps:	153/519 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 NINACQSIV----DAVRTTLGPRGMDKLIVDAHGKATISNDGATIMKLLEIIHPAAKTLVDIAKS 84
            ::..|.|::    ..||..|||.|...|.....|:..||..|..::..|.:.||.|:.::|...:
Zfish    11 SLQVCVSVLGPLESVVRRCLGPEGGSVLFTRDTGETLISRHGQRVLSTLHLEHPMARMVLDCVCA 75

  Fly    85 QDAEVGDGTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQLCMEKI-----NEMAVQIVE 144
            .....||||.|.:||....|:.    :::..|.|........|||....::     ||:...|:.
Zfish    76 HAKSTGDGTKSFILLLSALLRA----IQDSAHMRRKASWSNPALQNLANRLMALSRNELDDIIIH 136

  Fly   145 QSKDQQRALLEKCAATAMSSKLIHQQKDFFSRIVVDAVLSLDELLPLNMIG-IKKVTGGSLEE-- 206
            |             .|..:|.......|.....::|.::|          | |...||....|
Zfish   137 Q-------------VTPYASSYCSHHSDKLEHSILDYLIS----------GYISGRTGAGQAEIL 178

  Fly   207 SQLVSGVAFKK----------TFSYAGFEMAPKSYDNCKIALLNIELELKAERDNA---EIR--- 255
            ..::....:|.          :|.::.|.:.........:....:...|...||.:   |:|
Zfish   179 KHILCEFYYKSKRDQNTTETISFIHSHFNVLHTRVAGLPVGCSEVIEGLVVTRDWSVWTELRGPI 243

  Fly   256 -------------VDNVKE-YQKVVDAEW-----QILYNKLAKIHESGANVVLSKLPIGDVATQY 301
                         .||:.. :|:    :|     .|...|||.:.|...|||||.:...:...|:
Zfish   244 KALVLYESFGSSLGDNITVCFQQ----DWLSRTESITKQKLAYLLELQVNVVLSSVKQPECVLQW 304

  Fly   302 F------------ADR-DIFCAGRVPEEDLKRTMKACGGAVMTTANDIKPNVLGLCEHFEERQVG 353
            .            :|: |..|....||     |:.             .|..:.:.::.:..|:|
Zfish   305 ARMNHVALLECVDSDQLDFLCNINFPE-----TLS-------------HPQHIVMLKYCKRLQLG 351

  Fly   354 GERFNLFQGCPN----AKTSTLILRGGAEQFLEET---ERSLHDAIMIVRRTIKHD--------- 402
            |.|      |..    :...||:|...|...|::|   .|.:...:..:.||::.:
Zfish   352 GLR------CAQLGIYSNAHTLVLCAPAPGLLDQTVCVSRGVFLMLQHITRTLESNQFKSSSVDQ 410

  Fly   403 ------------------SVVAGGGAIEMELSKLLRDYSRTIAGKEQLLIAAIAKGLEIIPRQL 448
                              .|:..||..|..|...|  .:|..:..|...:  :|:.|..:||.|
Zfish   411 SQCTVSSQDLWRAVMQAGGVLPVGGVFEFLLHHFL--LTRHTSDPESCRL--LAEALLCVPRAL 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT7	NP_649835.1	chap_CCT_eta	2..524	CDD:274086	102/519 (20%)
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	102/519 (20%)
bbs10	XP_021323237.1	chaperonin_like	22..474	CDD:322083	100/508 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910