Protein Alignment Ir85a and grin2bb

DIOPT Version :9

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001121809.1
• Gene: grin2bb / 559976
• ZFINID: ZDB-GENE-061207-27
• Length: 1770
• Species: Danio rerio
• Alignment Length: 592
• Identity: 107/592 - (18%)
• Similarity: 196/592 - (33%)
• Gaps: 201/592 - (33%)

  Fly    67 QILKEVTKCDISNQNTPLEAVKDDGILMY--MVMITTNISQPLEL-------SLIRK-------- 114
            ::|:.:.......:|.   :..:||..|:  :|:|..|..:..|.       ||..|
Zfish   411 EVLRYLMNVTFEGRNL---SFSEDGFQMHPKLVIILLNKERQYERVGKWENGSLAMKYHVWPRFE 472

  Fly   115 -KSAAKHR--SHV---------FLLVRDADTVSDAWMRASFRQFWKIWLLNIVILYWRDGRLNAY 167
             .|.|:.|  .|:         |::|.|.|.:|...||
Zfish   473 LYSDAEEREDDHLSIVTLEEAPFVIVEDVDPLSGTCMR--------------------------- 510

  Fly   168 RYNPFMDNYLIPVDNKPNEVPTLEQLFPKTIPNMQRKPLRMC-------IYKDDVRAIFWRQGTI 225
                             |.||..:||..:.:.......::.|       |.|...:::.:.....
Zfish   511 -----------------NTVPCRKQLKLQNLTGDSGIYIKRCCKGFCIDILKKIAKSVKFTYDLY 558

  Fly   226 LGTDGLLAAYVAERLNATM--MITRPHSYNNHNLSSDICFLEVAKEYVDVAMNIRFLVP------ 282
            |.|:|    ...:::|.|.  |:......|.|.....:...|...|.:|      |.||
Zfish   559 LVTNG----KHGKKINGTWNGMVGEVVLKNAHMAVGSLTINEERSEVID------FSVPFIETGI 613

  Fly   283 DTFRKQAESTVSHTRDDLCVIVPKAKTAPTFWNIFRSFGSLVWALILVSVLVAN---VFCYILKS 344
            .....::..|||          |.|...|        |.:.||.::.|.:|:.:   ||.:...|
Zfish   614 SVMVSRSNGTVS----------PSAFLEP--------FSADVWVMMFVMLLIVSAVAVFVFEYFS 660

  Fly   345 EV--------GRVP----------MQLFAGAL---TMPMTQIPPNHSIRLFLIFWLYFGLLICSA 388
            .|        ||.|          :.|..|.:   ::|: |.|...:.::.:..|.:|.::..::
Zfish   661 PVGYNRCLADGREPGGPSFTIGKAIWLLWGLVFNNSVPV-QNPKGTTSKIMVSVWAFFAVIFLAS 724

  Fly   389 FKGNLTSMMVFQPYLPDINQLGALARSHYHIIIRPRHVKHIQHFLTLGHKHESRIREQMLEVSDT 453
            :..||.:.|:.:.|:..:..|......|.:....|.....:.:..|     |..||....|:
Zfish   725 YTANLAAFMIQEEYVDQVTGLSDKKFQHPNDFSPPFRFGTVPNGST-----ERNIRNNYKEM--- 781

  Fly   454 QMYEMMRNNDIRFAYLEKYHIARFQVNSRVH-MHLGRPLFHLMNSCLVPFHA-----VYIVPYGS 512
                        .:|:..:|  :..||..:| :..|:....:.::.::.:.|     ..:|..||
Zfish   782 ------------HSYMTSFH--QKNVNEALHSLKSGKLDAFIYDAAVLNYMAGRDEGCKLVTIGS 832

  Fly   513 PYL----GFLDSLIRSSHEFGFERYWDRIMNSAFIKSGVKVVNRRRGSGNDEPVVLKLQHFHAVF 573
            .|:    |:..::.:.|.       |.|.::.|.:        :..|.|..|.:.
Zfish   833 GYIFATTGYGIAIQKDSG-------WKRAVDLAIL--------QLFGDGEMEELE---------- 872

  Fly   574 ALWLVGI 580
            ||||.||
Zfish   873 ALWLTGI 879

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
grin2bb	NP_001121809.1	PBP1_iGluR_NMDA_NR2	107..470	CDD:107373	12/61 (20%)
		ANF_receptor	138..442	CDD:279440	6/33 (18%)
		PBP2_iGluR_NMDA_Nr2	482..882	CDD:270436	92/518 (18%)
		Lig_chan	636..908	CDD:278489	55/292 (19%)
		NMDAR2_C	919..1770	CDD:287527

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591412
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740