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Protein Alignment Ir85a and Grik2

DIOPT Version :9

Sequence 1:	NP_649833.1	Gene:	Ir85a / 41052	FlyBaseID:	FBgn0037630	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_062182.1	Gene:	Grik2 / 54257	RGDID:	2733	Length:	908	Species:	Rattus norvegicus

Alignment Length:	746	Identity:	131/746 - (17%)
Similarity:	247/746 - (33%)	Gaps:	261/746 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 IPLDLKKSSIVMVKMSQILCKARIKVLFVYFENQTSHEHTGQILKEV--------------TKCD 76
            :|.|.|.:..::.:|.      |.|...|.|:  .|||....|||:.              |..|
  Rat   204 LPADTKDAKPLLKEMK------RGKEFHVIFD--CSHEMAAGILKQALAMGMMTEYYHYIFTTLD 260

  Fly    77 ISNQNTPLEAVKDDGILM--YMVMIT--TNISQPLE-LSLIRKKSAAKHRSHVF--LLVRDADTV 134
            :...:  :|..:..|:.|  :.::.|  |.:|..:| .|:.|.::..|..|.:.  .:..||..:
  Rat   261 LFALD--VEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALM 323

  Fly   135 SDA--WMRASFRQF---------------WKI---WLLNIVILYWR--DGRLNAYRYNPFMDNYL 177
            .||  .:..:.:||               |:.   ::..|...:|.  .||:...:.|....::.
  Rat   324 YDAVHVVSVAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTDFD 388

  Fly   178 IPV--------------------------DNKPNEV------------PTLEQ---LFPKTIPNM 201
            :.|                          ..||..:            ..||:   ||.|:
  Rat   389 LDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKS---- 449

  Fly   202 QRKPL-------RMCIYKDDVRAIFWRQGTILG--------TDGLLAA----------------- 234
             .|||       ..||  |.:|.:    .||||        .||...|
  Rat   450 -DKPLYGNDRFEGYCI--DLLREL----STILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELID 507

  Fly   235 YVAERLNATMMITRPHSYNNHNLSSDICFLEVAKEYVDVAMNIRFLVPDTFRKQAESTVSHTRDD 299
            :.|:...|.:.||    |....:      ::.:|.::.:.::|.:..|:
  Rat   508 HKADLAVAPLAIT----YVREKV------IDFSKPFMTLGISILYRKPN---------------- 546

  Fly   300 LCVIVPKAKTAPTFWNIFRSFGSLVWALILVSVLVANVFCYIL----------------KSEVGR 348
                    .|.|..::........:|..:|::.|..:...:::                .|:|..
  Rat   547 --------GTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVE 603

  Fly   349 VPMQLF------AGALTMPMTQIPPNH-SIRLFLIFWLYFGLLICSAFKGNLTSMMVFQPYLPDI 406
            ....|.      .|||....:::.|.. |.|:....|.:|.|:|.|::..||.:.:..:.....|
  Rat   604 NNFTLLNSFWFGVGALMRQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPI 668

  Fly   407 NQLGALARSHYHIIIRPRHVKH--IQHFLTLGHKHESRI-------------REQMLEVSDTQMY 456
            :....||:.        ..:::  ::...|:....:|:|             |:.:|..|:.:..
  Rat   669 DSADDLAKQ--------TKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGI 725

  Fly   457 EMMRNNDIRFAYLEKYHIARFQVNSRVHM-HLGRPLFHLMNSCLVPFHAVYIV--PYGSPYLGFL 518
            :.:..:|  :|:|.:.....|......:: .:|    .|::|      ..|.|  |.||||...:
  Rat   726 QRVLTSD--YAFLMESTTIEFVTQRNCNLTQIG----GLIDS------KGYGVGTPMGSPYRDKI 778

  Fly   519 DSLIRSSHEFG-----FERYWDRIMNSAFIKSGVKVVNRRRGSG-----NDEPVVLKLQHFHAVF 573
            ...|....|.|     .|::|                   ||:|     :.|...|.:|:...:|
  Rat   779 TIAILQLQEEGKLHMMKEKWW-------------------RGNGCPEEESKEASALGVQNIGGIF 824

  Fly   574 ALWLVGIGMACIVLAWEHLTHNYNLAVTKRR 604
            .:...|:.::..|...|.|..:...|..::|
  Rat   825 IVLAAGLVLSVFVAVGEFLYKSKKNAQLEKR 855

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.