Protein Alignment Ir85a and grin2da

DIOPT Version :9

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_009292354.1
• Gene: grin2da / 449864
• ZFINID: ZDB-GENE-041008-124
• Length: 1916
• Species: Danio rerio
• Alignment Length: 569
• Identity: 103/569 - (18%)
• Similarity: 209/569 - (36%)
• Gaps: 161/569 - (28%)

  Fly   122 SHVFLLVRDADTVSDAWMRASFRQFWKIWLLNIV----------ILYWRDGRLNA-----YRYNP 171
            |::.|..||....:|.::...        ||:::          :.:|.:|.|..     .||.|
Zfish   388 SNITLSGRDYSFNNDGYLANP--------LLDVISYTAGRGWEEVGWWENGVLRLRYPPWSRYGP 444

  Fly   172 FMDNYLIPVDNKPN-EVPTLEQ---------------LFPKTIPNMQRKPLRMCIYKDDVRAI-F 219
            |    |.|:|:..: .|.|||:               ....::|  .|.||...:..:.:::: .
Zfish   445 F----LKPLDDSQHLRVVTLEERPFVIVEPADPGTGSCIRDSVP--CRLPLNNSMVVEGIQSMKH 503

  Fly   220 WRQGTILGTDGLLAAYVAERLNATMMITRPHSYN-----NHNLSSDICFLEVAKEYVDVAMNIRF 279
            ..:|..:.....||..|....:..::....|..|     |..:.      ||..:..|:|:. ..
Zfish   504 CCKGFCIDVLKRLAKIVGFTYDLYLVTNGRHGKNIDGQWNGMVG------EVVSKRADMAIG-SL 561

  Fly   280 LVPDTFRKQAESTVSHTRDDLCVIVPKAKTAPTFWNIFRSFGSLVWALILV---SVLVANVFCYI 341
            .:.:...:..|.:|......:.|:|.::....:.......:...||.::.|   ||:...||.:.
Zfish   562 TINEERSEVVEFSVPFVETGISVMVSRSNGTVSPSAFLEPYSPAVWVMMFVMCLSVVAVTVFIFE 626

  Fly   342 LKSEVGRVPMQLFAG------------------AL----TMPMTQIPPNHSIRLFLIFWLYFGLL 384
            ..|.|| ....|.:|                  ||    ::|: :.|...:.::.::.|.:|.::
Zfish   627 FFSPVG-YNRSLQSGKTAGGSKFTIGKSIWLLWALVFNNSVPV-ENPRGTTSKIMVLVWAFFAVI 689

  Fly   385 ICSAFKGNLTSMMVFQPYLPDINQLGALARSHYHIIIRPRHVKHIQHFLTLGHKHESRIREQMLE 449
            ..:::..||.:.|:.:.|:..::.|..               |..||
Zfish   690 FLASYTANLAAFMIQEEYIDTVSGLSD---------------KKFQH------------------ 721

  Fly   450 VSDTQMYEMMR---------NNDIRFAY--LEKYHIARFQ--VNSRV-HMHLGRPLFHLMNSCLV 500
              .|:.|..:|         ..:||..|  :.:|.:...|  |...: ::..|:....:.::.::
Zfish   722 --PTEQYPPLRFGTVPNGSTEENIRSNYPNMHQYMVRNNQRGVEDAIENLKTGKLDAFIYDAAVL 784

  Fly   501 PFHA-------VYIVPYGSPY--LGFLDSLIRSSHEFGFERYWDRIMNSAFIK----SGVKVVNR 552
            .:.|       |..:..|..:  .|:..:|.::|.       |.|.::.|.::    ..:.::.|
Zfish   785 NYMARKDEGCKVMTIGSGKVFATTGYGVALHKNSR-------WKRPLDLALLQLVGDDEIDMLER 842

  Fly   553 RRGSG---NDEPVV----LKLQHFHAVFALWLVGIGMACIVLAWEHLTH 594
            ...||   ||:..|    |.:.:...||.:.||.:|::.:|.|||||.:
Zfish   843 LWLSGICHNDKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLVY 891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
grin2da	XP_009292354.1	PBP1_iGluR_NMDA_NR2	42..441	CDD:107373	10/60 (17%)
		PBP2_iGluR_NMDA_Nr2	452..851	CDD:270436	71/451 (16%)
		HisJ	<507..>590	CDD:223904	15/89 (17%)
		Lig_chan	605..877	CDD:278489	56/315 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591655
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740