Protein Alignment Ir85a and GluRIA

DIOPT Version :9

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_476855.1
• Gene: GluRIA / 38742
• FlyBaseID: FBgn0004619
• Length: 991
• Species: Drosophila melanogaster
• Alignment Length: 754
• Identity: 120/754 - (15%)
• Similarity: 247/754 - (32%)
• Gaps: 255/754 - (33%)

  Fly     8 HILLLAILVNLAGTRENHIPLDLKKSSIVMVKMSQILCKARIKVLFVYFENQTSHEHTGQILKEV 72
            |.||..:::      :||.|.|:.:...:.:...:|:...| :.:..:.:::...|.:||...:
  Fly   258 HYLLSGLVM------DNHWPSDVVEFGAINITGFRIVDSNR-RAVRDFHDSRKRLEPSGQSQSQ- 314

  Fly    73 TKCDISNQNTP--LEAVKDDGILMY-MVMITTNISQPLELSLIRKK------SAAKHRSH----- 123
                  |...|  |.|:.....||| .|.:......    .::|||      :..:.|||
  Fly   315 ------NAGGPNSLPAISAQAALMYDAVFVLVEAFN----RILRKKPDQFRSNHLQRRSHGGSSS 369

  Fly   124 ---------VFLLVRDADTVSDAWMRASFRQFWKI--------------------------WLLN 153
                     ..||  |.:| |..|: ..:.|..||                          :.|:
  Fly   370 SSATGTNESSALL--DCNT-SKGWV-TPWEQGEKISRVLRKVEIDGLSGEIRFDEDGRRINYTLH 430

  Fly   154 IV----------ILYWRD--GRLNAYRYNPFMDNYLIPVDNKPNEVPTLEQLFPKTIPNMQRKP- 205
            :|          :..|||  |.|..:.:     ||.....:........::.....:.::..:|
  Fly   431 VVEMSVNSTLQQVAEWRDDAGLLPLHSH-----NYASSSRSASASTGDYDRNHTYIVSSLLEEPY 490

  Fly   206 --LRMCIYKDDVRAIFWRQGTILGTD----------GLLAAYVAERLNATMMITRPHSYNNHNLS 258
              |:...|.:          :::|.|          .:|||.:.  :...:.:.:..:|...|..
  Fly   491 LSLKQYTYGE----------SLVGNDRFEGYCKDLADMLAAQLG--IKYEIRLVQDGNYGAENQY 543

  Fly   259 S----DICFLEVAKEYVDVAMNIRFLVPDTFRKQAESTVSHTRD----DLCVIVPK-AKTAPTFW 314
            :    |....|:.::..|:|::..     |...:.|..:..::.    .:.:::.| .|..|..:
  Fly   544 APGGWDGMVGELIRKEADIAISAM-----TITAERERVIDFSKPFMTLGISIMIKKPVKQTPGVF 603

  Fly   315 NIFRSFGSLVWALILVSVLVANVFCYIL---------------KSEVGRVPMQLFAGA-LTMPMT 363
            :........:|..:::|.:..:...|.:               .....:.|..:..|| |:.|..
  Fly   604 SFLNPLSQEIWISVILSYVGVSFVLYFVTRFPPYEWRIVRRPQADSTAQQPPGIIGGATLSEPQA 668

  Fly   364 QIPPN------------HSIRLFL-----------------IFWLYFGLLICSAFKGNLTSMMVF 399
            .:||.            :|:..|:                 ..|.:|.:::.|::..||.:.:..
  Fly   669 HVPPVPPNEFTMLNSFWYSLAAFMQQGCDITPPSIAGRIAAAVWWFFTIILISSYTANLAAFLTV 733

  Fly   400 QPYL------------PDINQLGALARSHYHIIIRPR---------HVKHIQHFLTLGHKHESRI 443
            :..:            .|:|....|..|.:....|.:         ::...||...  |.::..|
  Fly   734 ERMVAPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMNANQHHSV--HTYDEGI 796

  Fly   444 REQMLEVSDTQMYEMMRNNDIRFAYL-----EKYHIARFQVNSRV---HMHLGRPL----FHLMN 496
            |.             :|.:..::|.|     .:|      ||:|.   .|.:||.:    |.:
  Fly   797 RR-------------VRQSKGKYALLVESPKNEY------VNARPPCDTMKVGRNIDTKGFGV-- 840

  Fly   497 SCLVPFHAVYIVPYGSPYLGFLDSLIRSSHEFG-----FERYWDRIMNSAFIKSGVKVVNRRRGS 556
                      ..|.|||....|:..:.:..|.|     ..::|       |.|:... :::...:
  Fly   841 ----------ATPIGSPLRKRLNEAVLTLKENGELLRIRNKWW-------FDKTECN-LDQETST 887

  Fly   557 GNDEPVVLKLQHFHAVFALWLVGIGMACIVLAWEHLTHN 595
            .|:    |.|.:...::.:.:.|:.:|.||...|....|
  Fly   888 PNE----LSLSNVAGIYYILIGGLLLAVIVAIMEFFCRN 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..453	CDD:107375	41/216 (19%)
		ANF_receptor	53..434	CDD:279440	37/197 (19%)
		PBP2_iGluR_AMPA	477..879	CDD:270433	67/458 (15%)
		Lig_chan	612..907	CDD:278489	51/339 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462552
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740