DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir85a and Ir64a

DIOPT Version :9

Sequence 1:	NP_649833.1	Gene:	Ir85a / 41052	FlyBaseID:	FBgn0037630	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_647962.1	Gene:	Ir64a / 38616	FlyBaseID:	FBgn0035604	Length:	859	Species:	Drosophila melanogaster

Alignment Length:	432	Identity:	83/432 - (19%)
Similarity:	139/432 - (32%)	Gaps:	152/432 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QWLKHILLLAILVNLAGTRENHIPLDLKKSSIVMVKMSQILCKARIKVLF------VYFENQTSH 62
            :||:.:|.:..|..:|       .:||...::    ..:.|..|..|:|:      :..|:...|
  Fly   141 EWLEGVLRMEALRQIA-------VVDLACGAV----SRRFLELASAKMLYSEKFHWLLIEDFAWH 194

  Fly    63 EHTGQILKEVTKCD---ISNQNTP---LEAVKDD----------GILMYMVMITTNISQPLELSL 111
            ..| |..:...|.|   :..:..|   ::|..|:          |:.:||         ..||:|
  Fly   195 GRT-QTAEGSGKRDDGEMEEEEPPGQQIQATDDEDLPSIESFLGGMNLYM---------NTELTL 249

  Fly   112 IRKKSAAKHRSHVFLLVRDADTVSDAWMRASFRQFWKIWLLNIVILYWRDGRLNAYRYNPFMDNY 176
            .::.|.|.|.           |:.|.|              |..:.|  .|.:|......|
  Fly   250 AKRMSEAAHY-----------TLFDVW--------------NPGLNY--GGHVNLTEIGSF---- 283

  Fly   177 LIPVDNKPNEVPTLEQLFPKTIPNMQRKPLRMCIYKDDVRAIFWRQGTILGTDGLLAAYVAERLN 241
                  .|.|...|...| :|...::|   ||.:....||.              :.....:.:.
  Fly   284 ------TPTEGIQLHTWF-RTTSTVRR---RMDMQHARVRC--------------MVVVTNKNMT 324

  Fly   242 ATMMITRPHSYNNHNLSSDICFLEVAKEY-VDVAMNIRFLVPDTF---RKQAESTVSHTR-DDLC 301
            .|:|....|:.:.|        ::....: .::.|.:|.:...||   |..:...|.:.| |.:.
  Fly   325 GTLMYYLTHTMSGH--------IDTMNRFNFNLLMAVRDMFNWTFVLSRTTSWGYVKNGRFDGMI 381

  Fly   302 VIVPKAKT----APTF---------------WN-----IFR--------------SFGSLVWALI 328
            ..:.:.:|    ||.|               |:     |||              .|.:.||.||
  Fly   382 GALIRNETDIGGAPIFYWLERHKWIDVAGRSWSSRPCFIFRHPRSTQKDRIVFLQPFTNDVWILI 446

  Fly   329 L-VSVLVANVFCYILKSEVGRVPMQLFAGALTMPMTQIPPNH 369
            : ..||...:..::...|...||..  ..||..|....||.|
  Fly   447 VGCGVLTVFILWFLTTIEWKLVPHD--GSALIKPKGGAPPRH 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	23/113 (20%)
Ir64a	NP_647962.1	Lig_chan	563..828	CDD:278489
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462936
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830