Protein Alignment Ir85a and GluRIIC

DIOPT Version :10

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Alignment Length: 639
• Identity: 117/639 - (18%)
• Similarity: 201/639 - (31%)
• Gaps: 234/639 - (36%)

  Fly   115 KSAAKHRSHVFLLVRDA-DTVSDAWMRASFRQFW------------------KIWLL-------- 152
            :|:...|:.:..|:.|| ...:.:|..|||  |:                  :.|.:
  Fly   297 ESSDPPRTLIHDLIHDALQLFAQSWRNASF--FYPDRMVVPRITCDFAASGGRTWAMGRYLARLM 359

  Fly   153 ------------NIVILYWRDGR---LNAYRYNPFMDNYLIPVDNKPNEVPTLEQLFPKTIPNMQ 202
                        ..::.:..||:   .|...|:| :|...|.:.:...::..|         |:.
  Fly   360 KGTSGVNNTNFRTSILQFDEDGQRITFNIEVYDP-LDGIGIAIWDPRGQITQL---------NVD 414

  Fly   203 RKPLRMCIYKDDVRAIFWRQGTILGTDGLLAAYVAERLNATMMITRPH-SYNNH----NLSSDIC 262
            .|..:..||:                       ||.|:..      |: |||..    ||:.:..
  Fly   415 VKAQKKMIYR-----------------------VATRIGP------PYFSYNETARELNLTGNAL 450

  Fly   263 FLEVAKEYVD-VAMNIRF---LVP---------DTFRKQAESTVSHTRDD-----LC--VIVPKA 307
            :...|.:.:| :|.::.|   .||         |...||....:....::     :|  .|....
  Fly   451 YQGYAVDLIDAIARHVGFEYVFVPVADQQYGKLDKETKQWNGIIGEIINNDAHMGICDLTITQAR 515

  Fly   308 KTAPTFWNIFRS-----------------------FGSLVWALILVSVLVANVFCYILKSEVGRV 349
            |||..|...|..                       ||..||..||:||.|..    .||:.|.|:
  Fly   516 KTAVDFTVPFMQLGVSILAYKSPHVEKTLDAYLAPFGGEVWIWILISVFVMT----FLKTIVARI 576

  Fly   350 --------------PMQL-------------FAGALTMPMTQIPPNHSIRLFLIFWLYFGLLICS 387
                          |..|             .|..:|.....:|.:..:|:|...|..|.::|.:
  Fly   577 SKMDWENPHPCNRDPEVLENQWRIHNTGWLTVASIMTAGCDILPRSPQVRMFEATWWIFAIIIAN 641

  Fly   388 AFKGNLTSMMVFQPYLPDINQLGALARSHYHIIIRPRHVKHIQHFLTL--GHKHESRIREQMLEV 450
            ::..||.:.:........|..|..|:..        :.||    |.|:  |..:      .:|..
  Fly   642 SYTANLAAFLTSSKMEGSIANLKDLSAQ--------KKVK----FGTIYGGSTY------NLLAD 688

  Fly   451 SDTQMYEM---MRNNDIRFAYLEKYHIARFQVNSRVHMHLGRPLFHLMNSCLVPFHA-------- 504
            |:..:|.:   :.|||...||.:.    ..:...||..:.|..:| ||.:..:.:|.
  Fly   689 SNETVYRLAFNLMNNDDPSAYTKD----NLEGVDRVRKNRGDYMF-LMETTTLEYHREQNCDLRS 748

  Fly   505 ----------VYIVPYGSPYLGFLDSLIRSSHEFG-----FERYWDRIMNSAFIKSGVKVVNRRR 554
                      ...||:|:.|...|...|....|.|     .:::|.....|.|
  Fly   749 VGEKFGEKHYAIAVPFGAEYRSNLSVAILKLSERGELYDLKQKWWKNPNASCF------------ 801

  Fly   555 GSGNDEP-----VVLKLQHFHAVFALWLVGIGMACIVLAWEHLTHNYNLAVTKR 603
                :||     ..:..:....:|.....||.:|.::...|.|.:...:|:.:|
  Fly   802 ----EEPDPDATPDMTFEELRGIFYTLYAGILIAFLIGITEFLVYVQQVALEER 851

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	18/114 (16%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	82/426 (19%)
		Lig_chan	554..827	CDD:459656	60/315 (19%)