back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir85a and Gria2

DIOPT Version :9

Sequence 1:	NP_649833.1	Gene:	Ir85a / 41052	FlyBaseID:	FBgn0037630	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_001077280.1	Gene:	Gria2 / 29627	RGDID:	61862	Length:	883	Species:	Rattus norvegicus

Alignment Length:	366	Identity:	65/366 - (17%)
Similarity:	127/366 - (34%)	Gaps:	80/366 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   272 DVAMNIRFLVPDTFRKQAESTVSHTRD----DLCVIVPK-AKTAPTFWNIFRSFGSLVWALILVS 331
            |:|     :.|.|.....|..:..::.    .:.:::.| .|:.|..::........:|..|:.:
  Rat   494 DIA-----IAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFA 553

  Fly   332 VLVANVFCYILK------------------------SEVGRVPMQLFA-GALTMPMTQIPPNH-S 370
            .:..:|..:::.                        :|.|......|: ||.......|.|.. |
  Rat   554 YIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLS 618

  Fly   371 IRLFLIFWLYFGLLICSAFKGNLTSMMVFQPYLPDINQLGALARSHYHIIIRPRHVKHIQHFLTL 435
            .|:....|.:|.|:|.|::..||.:.:..:..:..|.....|:          :..:.....|..
  Rat   619 GRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLS----------KQTEIAYGTLDS 673

  Fly   436 GHKHESRIREQMLEVSDTQMYEMMRNNDIR-FAYLEKYHIARFQVNSRVHMHLGRPLFHLMNSCL 499
            |...|. .|...:.|.| :|:..||:.:.. |.......:||.:.:...:.:|   |...||..:
  Rat   674 GSTKEF-FRRSKIAVFD-KMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYL---LESTMNEYI 733

  Fly   500 ---VPFHAVYI------------VPYGSPYLGFLDSLIRSSHEFGFERYWDRIMNSAFIKSGVKV 549
               .|...:.:            .|.||.....::..:...:|.|.   .|::.|..:...|
  Rat   734 EQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGL---LDKLKNKWWYDKG--- 792

  Fly   550 VNRRRGSG----NDEPVVLKLQHFHAVFALWLVGIGMACIV 586
               ..|||    .::...|.|.:...||.:.:.|:|:|.:|
  Rat   793 ---ECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLV 830

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.