DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ir85a and GRIK4

DIOPT Version :9

Sequence 1:NP_649833.1 Gene:Ir85a / 41052 FlyBaseID:FBgn0037630 Length:605 Species:Drosophila melanogaster
Sequence 2:NP_001269399.1 Gene:GRIK4 / 2900 HGNCID:4582 Length:956 Species:Homo sapiens


Alignment Length:233 Identity:41/233 - (17%)
Similarity:77/233 - (33%) Gaps:66/233 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   196 KTIPNMQRKPLRMCIYKDDVRAIFWRQGTILGTDGLLAAYVAERLNATMMITRPHSYNNHNLSSD 260
            |.:..:.|...::.:..|.|..:....||..|..|.|.|..|:...|.:.||.....        
Human   453 KELAEILRFNYKIRLVGDGVYGVPEANGTWTGMVGELIARKADLAVAGLTITAEREK-------- 509

  Fly   261 ICFLEVAKEYVDVAMNIRFLVPDTFRKQAESTVSHTRDDLCVIVPKAKTAPTFWNIFRSFGSLVW 325
              .::.:|.::.:.::|.:.| ...||                       |.:::....|...||
Human   510 --VIDFSKPFMTLGISILYRV-HMGRK-----------------------PGYFSFLDPFSPGVW 548

  Fly   326 ALILVSVLVANVFCYILKSEVGRV-PMQLFA---------------------------GALTMPM 362
            ..:|::.|..:...::    |.|: |.:.::                           |.:....
Human   549 LFMLLAYLAVSCVLFL----VARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGS 609

  Fly   363 TQIPPNHSIRLFLIFWLYFGLLICSAFKGNLTSMMVFQ 400
            |..|...|.|.....|..|.|:|.|::..||.:.:..|
Human   610 TIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQ 647

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir85aNP_649833.1 None
GRIK4NP_001269399.1 PBP1_iGluR_Kainate_KA1_2 26..400 CDD:107389
ANF_receptor 43..382 CDD:279440
PBP2_iGluR_kainate_KA1 415..785 CDD:270442 41/233 (18%)
Lig_chan 547..816 CDD:278489 20/105 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 863..889
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 931..956
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165155773
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1052
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.740

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