Protein Alignment Ir85a and GRIA1

DIOPT Version :9

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001244950.1
• Gene: GRIA1 / 2890
• HGNCID: 4571
• Length: 916
• Species: Homo sapiens
• Alignment Length: 378
• Identity: 67/378 - (17%)
• Similarity: 126/378 - (33%)
• Gaps: 104/378 - (27%)

  Fly   272 DVAMNIRFLVPDTFRKQAESTVSHTRD----DLCVIVPK-AKTAPTFWNIFRSFGSLVWALILVS 331
            |||     :.|.|.....|..:..::.    .:.:::.| .|:.|..::........:|..|:.:
Human   497 DVA-----VAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFA 556

  Fly   332 VLVANVFCYIL------------------------KSEVGRVPMQLFA-GALTMPMTQIPPNH-S 370
            .:..:|..:::                        .:|.|......|: ||.......|.|.. |
Human   557 YIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLS 621

  Fly   371 IRLFLIFWLYFGLLICSAFKGNLTSMMVFQPYLPDINQLGALARSHYHIIIRPRHVKHIQHFLTL 435
            .|:....|.:|.|:|.|::..||.:.:..:..:..|.....||:
Human   622 GRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK--------------------- 665

  Fly   436 GHKHESRIREQMLEVSDTQMYEMMRNNDI-----RFAYLEKYHIARFQVNS-----RVHMHLGRP 490
                ::.|....||...|:  |..|.:.|     .:.|::....:.|...:     ||....|:.
Human   666 ----QTEIAYGTLEAGSTK--EFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKY 724

  Fly   491 LFHL---MNSCL---VPFHAVYI------------VPYGSPYLGFLDSLIRSSHEFGFERYWDRI 537
            .:.|   ||..:   .|...:.:            .|.||.....::..:...:|.|.   .|::
Human   725 AYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGL---LDKL 786

  Fly   538 MNSAFIKSGVKVVNRRRGSG----NDEPVVLKLQHFHAVFALWLVGIGMACIV 586
            .|..:...|      ..|||    .|:...|.|.:...||.:.:.|:|:|.:|
Human   787 KNKWWYDKG------ECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLV 833

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
GRIA1	NP_001244950.1	PBP1_iGluR_AMPA_GluR1	36..399	CDD:107385
		ANF_receptor	47..382	CDD:279440
		PBP2_iGluR_AMPA_GluR1	416..797	CDD:270447	55/340 (16%)
		Lig_chan	548..827	CDD:278489	54/314 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156054
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740