Protein Alignment Ir85a and Grin2c

DIOPT Version :9

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_036707.3
• Gene: Grin2c / 24411
• RGDID: 2739
• Length: 1250
• Species: Rattus norvegicus
• Alignment Length: 545
• Identity: 95/545 - (17%)
• Similarity: 202/545 - (37%)
• Gaps: 188/545 - (34%)

  Fly   159 WRDGRLNAYRYNPFMDNY---LIP-VDNKPNEVPTLEQLFPKTIPNMQRKPLRMCIYKDDVRAIF 219
            |..|.|  |...|....|   |.| ||::...|.|||:           :|..:....|.
  Rat   388 WDHGVL--YMKYPVWPRYSTSLQPVVDSRHLTVATLEE-----------RPFVIVESPDP----- 434

  Fly   220 WRQGTILGTDGLLAAYVAERLNATMMITRPHSYNNHNLS--SDIC----FLEVAKEYVDVAMNIR 278
                   ||.|.:...|..|..:.      |::::.:|:  :.:|    .:::.|:...|   ::
  Rat   435 -------GTGGCVPNTVPCRRQSN------HTFSSGDLTPYTKLCCKGFCIDILKKLAKV---VK 483

  Fly   279 F----------------------LVPDTFRKQAES-----TVSHTRDDLC-VIVPKAKTAPTFWN 315
            |                      ::.:.:.|:|:.     |::..|.::. ..||..:|..:..
  Rat   484 FSYDLYLVTNGKHGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPFVETGISVM- 547

  Fly   316 IFRSFGSL------------VWALILV---SVLVANVFCY-----------ILKSE--------V 346
            :.||.|::            ||.::.|   :|:...||.:           :.|.:        :
  Rat   548 VSRSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLTKGKKPGGPSFTI 612

  Fly   347 GRVPMQLFAGAL--TMPMTQIPPNHSIRLFLIFWLYFGLLICSAFKGNLTSMMVFQPYLPDINQL 409
            |:....|:|...  ::|: :.|...:.::.::.|.:|.::..:::..||.:.|:.:.|   |:.:
  Rat   613 GKSVWLLWALVFNNSVPI-ENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQY---IDTV 673

  Fly   410 GALARSHYHIIIRPRHVKHIQHFLTLGHKHESRIREQMLEVSDTQMYEMMRNNDIRFAYLEKY-H 473
            ..|:...:.   ||:.......|.|:.:....|                    :||..|.:.: |
  Rat   674 SGLSDKKFQ---RPQDQYPPFRFGTVPNGSTER--------------------NIRSNYRDMHTH 715

  Fly   474 IARFQVNS----RVHMHLGRPLFHLMNSCLVPFHA-----VYIVPYGSPYL----GFLDSLIRSS 525
            :.:|...|    ...:.:|:....:.::.::.:.|     ..:|..||..:    |:..::.:.|
  Rat   716 MVKFNQRSVEDALTSLKMGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDS 780

  Fly   526 HEFGFERYWDRIMNSAFIK---------------SGV------KVVNRRRGSGNDEPVVLKLQHF 569
            |       |.|.::.|.::               ||:      :|::.:          |.:.:.
  Rat   781 H-------WKRAIDLALLQLLGDGETQKLETVWLSGICQNEKNEVMSSK----------LDIDNM 828

  Fly   570 HAVFALWLVGIGMACIVLAWEHLTH 594
            ..||.:.||.:|:|.:|.|||||.:
  Rat   829 AGVFYMLLVAMGLALLVFAWEHLVY 853

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
Grin2c	NP_036707.3	PBP1_iGluR_NMDA_NR2	41..397	CDD:380601	4/10 (40%)
		PBP2_iGluR_NMDA_Nr2	413..813	CDD:270436	71/466 (15%)
		NMDAR2_C	850..>925	CDD:402274	2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350133
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740