Protein Alignment Ir85a and Grin3a

DIOPT Version :9

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001263284.1
• Gene: Grin3a / 242443
• MGIID: 1933206
• Length: 1135
• Species: Mus musculus
• Alignment Length: 551
• Identity: 101/551 - (18%)
• Similarity: 175/551 - (31%)
• Gaps: 173/551 - (31%)

  Fly   159 WRDGRL---------NAYRY-------------------NPFM------DNYLIP-----VDNKP 184
            |:.||:         .|.|:                   :||:      |..|.|     :|...
Mouse   484 WQGGRIVMDSGIWPEQAQRHKTHFHHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMT 548

  Fly   185 NEVPTLEQLFPKTIPNMQRKPLRM--CIY----------KDDVRAIF------------WRQGTI 225
            |:...|:.||.....:....|::.  |.|          .:|:...|            |:.|..
Mouse   549 NDSSILDSLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNGHW 613

  Fly   226 LGTDG-LLAAYVAERLNATMMITRPHSYNNHNLSSDICFLEVAKEYVDVAMNIRFLVPDTFRKQA 289
            .|..| ||:.      .|.|.:|   |::.:...|.:               |.|..|  |...:
Mouse   614 TGLVGDLLSG------TANMAVT---SFSINTARSQV---------------IDFTSP--FFSTS 652

  Fly   290 ESTVSHTRDDLCVIVPKAKTAPTFWNIFRSFGSLVWALILVSVLVANVF--CYILKSEVGRVP-- 350
            ...:..|||....|  .|...|..|.        :|..|.|::.:..:|  .|..||..|..|
Mouse   653 LGILVRTRDTAAPI--GAFMWPLHWT--------MWLGIFVALHITAIFLTLYEWKSPFGMTPKG 707

  Fly   351 -----MQLFAGALTMPMTQI--------PPNHSIRLFLI-FWLYFGLLICSAFKGNLTSMMVFQP 401
                 :..|:.||.:....:        ||......||: .|..|.:...|.:..||.::||.:.
Mouse   708 RNRNKVFSFSSALNVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEK 772

  Fly   402 YLPDINQLGALARSHYHIIIRPRHVKHIQHFLTLGHKHESRIREQMLEVSDTQMYEMMRNNDIRF 466
            ...:::.            |....:.|.......|...||. .|..:..|..:|:|.||..::..
Mouse   773 IYEELSG------------IHDPKLHHPSQGFRFGTVRESS-AEDYVRQSFPEMHEYMRRYNVPA 824

  Fly   467 ----------------AYLEKYHIARFQVNSRVHMHL---GRPLFHLMNSCLVPFHAVYIVPYGS 512
                            |::....:..::|:......|   |:|.       .:..:.:.:.| .|
Mouse   825 TPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPF-------AIEGYGIGLPP-NS 881

  Fly   513 PYLGFLDSLIRSSHEFGF----ERYWDRIMNSAFIKSGVKVVNRRRGSGNDEPVVLKLQHFHAVF 573
            |....:..||......||    ...|.:::...           :|.....|.:.:.::||..:|
Mouse   882 PLTSNISELISQYKSHGFMDVLHDKWYKVVPCG-----------KRSFAVTETLQMGIKHFSGLF 935

  Fly   574 ALWLVGIGMACIVLAWEHLTHNYNLAVTKRR 604
            .|..:|.|::.:....||:.:...|...|.:
Mouse   936 VLLCIGFGLSILTTIGEHIVYRLLLPRIKNK 966

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
Grin3a	NP_001263284.1	PBP1_iGluR_NMDA_NR3	30..497	CDD:107372	3/12 (25%)
		PBP2_iGluR_NMDA_Nr3	512..908	CDD:270438	83/452 (18%)
		Lig_chan	676..942	CDD:278489	53/305 (17%)
		PPP2CB binding site. /evidence=ECO:0000250|UniProtKB:Q9R1M7	951..987		4/16 (25%)
		GIT1-binding. /evidence=ECO:0000250|UniProtKB:Q9R1M7	1082..1115

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846517
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830