DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir85a and glr-7

DIOPT Version :9

Sequence 1:	NP_649833.1	Gene:	Ir85a / 41052	FlyBaseID:	FBgn0037630	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_001337310.1	Gene:	glr-7 / 180547	WormBaseID:	WBGene00001618	Length:	885	Species:	Caenorhabditis elegans

Alignment Length:	396	Identity:	73/396 - (18%)
Similarity:	145/396 - (36%)	Gaps:	105/396 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   272 DVAMNIRFLVPDTFRKQAESTVSHTRD--DLCVIVPKAKTAPTFWNIFRSFGSL---VWALILVS 331
            |:|     |.|.:...:.|:.|..|..  ||.......|.|...:::|:....|   ||..|:.:
Worm   446 DIA-----LAPLSVMAERENDVDFTVPYYDLVGTTILMKKADVEYSLFKFMKVLEWPVWLCIVAA 505

  Fly   332 VLVANVFCYIL---------------KSEVGRVPMQLFAGALTMPMTQI--------PPNHSIRL 373
            .|..::..:|.               ::::.:....| ...|...||.:        |.|.|.||
Worm   506 YLFTSILLWIFDRFSPYSFTNNKERYQNDIEKRQFSL-KECLWFCMTSLTPQGGGEAPKNISGRL 569

  Fly   374 FLIFWLYFGLLICSAFKGNLTSMMVFQPYLPDINQLGALARSHYHIIIRPRHVKHIQHFLTLGHK 438
            ....|..||.:|.:::..||.:.:........|:.|..||:.:           .|::....|..
Worm   570 VAATWWLFGFIIIASYTANLAAFLTVSRLEQPISSLDDLAKQY-----------KIEYAPIKGSA 623

  Fly   439 HESRIREQMLEVSDT--QMYEMMRNNDIR------------FAYLEKY-HIARFQVNSRVHMHLG 488
            .|:..| :|.|:.:|  .|::.|..|:..            :...:|: ::.|:...|::.:::.
Worm   624 SETYFR-RMAEIEETFYNMWKEMSLNESMSPRDRAKLAVWDYPVSDKFTNMWRYMQESKLPVNMD 687

  Fly   489 RPLFHLMNSCLVPFHAVYIVPYGSPYLGFLD----------SLIRSSHEFGFERYWDRIMNSAFI 543
            ..:..::||.           .|..::|...          :|.:...||..:.|...:.:...:
Worm   688 TAVDRVLNSV-----------DGFAFIGDATEIKYAALTNCNLQQVGTEFSRKPYAIAVQSGHIL 741

  Fly   544 KSGVK-----VVNRRR------------------GSGNDEPVVLKLQHFHAVFALWLVGIGMACI 585
            |..:.     ::|.||                  ...:||...:.:|:...||.:.|.||.::.:
Worm   742 KDKISSAILMLLNERRLETLKEKWWTDNPNKVSCPDSSDESDGISIQNIGGVFIVILAGIALSIV 806

  Fly   586 VLAWEH 591
            .||:|:
Worm   807 TLAFEY 812

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
glr-7	NP_001337310.1	Periplasmic_Binding_Protein_Type_1	<102..>220	CDD:324556
glr-7	NP_001337310.1	PBP2_iGluR_putative	373..767	CDD:270435	62/349 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810