Protein Alignment Ir85a and gria2a

DIOPT Version :10

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_005170953.1
• Gene: gria2a / 170450
• ZFINID: ZDB-GENE-020125-3
• Length: 893
• Species: Danio rerio
• Alignment Length: 533
• Identity: 95/533 - (17%)
• Similarity: 164/533 - (30%)
• Gaps: 195/533 - (36%)

  Fly   175 NYLIPVDNKPNEVP--------------TLEQLFPKTIPNMQRKPLRMCIYKDDVRAIFWRQGTI 225
            ||.:.|....|..|              |...|||.....|:.|                   |:
Zfish   364 NYTVNVMELKNSGPVKIGYWNEMDKMAVTKSDLFPNDTMGMENK-------------------TV 409

  Fly   226 LGTDGLLAAYVAERLNATMMITRPHSYNNHNLSSDICFLEVAKEYVDVAMNIRFLVPDTF-RKQA 289
            :.|..|.|.||..:.||. :.|....|..:.:  |:. .|:|| :......:|.:....: .:.|
Zfish   410 IVTTILEAPYVMLKKNAE-LFTDNERYEGYCV--DLA-AEIAK-HCGFKYQLRIVADGKYGARDA 469

  Fly   290 ES----------------------TVSHTRDD------------LCVIVPK-AKTAPTFWNIFRS 319
            |:                      |::..|::            :.:::.| .|:.|..::....
Zfish   470 ETKIWNGMVGELVYGKADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDP 534

  Fly   320 FGSLVWALILVSVLVANVFCYILKSEVGRVPMQLFAGALTMPMT---------QIPPNHSIRLFL 375
            ....:|..|        ||.||      .|.:.||..:...|..         |:.|:.|...|.
Zfish   535 LAYEIWMCI--------VFAYI------GVSVVLFLVSRFSPYEWHTEEFEDGQLGPSESTNEFG 585

  Fly   376 IF------------------------------WLYFGLLICSAFKGNLTSMMVFQPYLPDINQLG 410
            ||                              |.:|.|:|.|::..||.:.:..:..:..|....
Zfish   586 IFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAE 650

  Fly   411 ALARSHYHIIIRPRHVKHIQHFLTLGHKHESRIREQMLEVSDTQMYEMMRNN-----DIRFAYLE 470
            .||:                         ::.|....|:...|:  |..|.:     |..:.|::
Zfish   651 DLAK-------------------------QTEIAYGTLDAGSTK--EFFRRSKIALFDKMWQYMK 688

  Fly   471 KYHIARFQVNS-----RVHMHLGRPLFHL---MNSCL---VPFHAVYI------------VPYGS 512
            ....:.|..|:     ||....|:..:.|   ||..:   .|...:.:            .|.||
Zfish   689 SAEPSVFVKNTVEGVLRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGS 753

  Fly   513 PYLGFLDSLIRSSHEFGFERYWDRIMNSAFIKSGVKVVNRRRGSGNDE----PVVLKLQHFHAVF 573
            .....::..:...:|.|.   .|::.|..:...|      ..|||..|    ...|.|.:...||
Zfish   754 ALRNAVNLAVLKLNEQGL---LDKLKNKWWYDKG------ECGSGGGESKEKTSALSLSNVAGVF 809

  Fly   574 ALWLVGIGMACIV 586
            .:.:.|:|:|.:|
Zfish   810 YILVGGLGLAMLV 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
gria2a	XP_005170953.1	Periplasmic_Binding_Protein_type1	23..393	CDD:471960	5/28 (18%)
		PBP2_iGluR_AMPA	406..783	CDD:270433	72/444 (16%)