Protein Alignment Ir85a and Grid2

DIOPT Version :9

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_032193.1
• Gene: Grid2 / 14804
• MGIID: 95813
• Length: 1007
• Species: Mus musculus
• Alignment Length: 460
• Identity: 81/460 - (17%)
• Similarity: 162/460 - (35%)
• Gaps: 109/460 - (23%)

  Fly   187 VPTLEQLFPKTIPNMQRKPLRMCIYKDDVRAIFWRQGTILGTDGLLAAYVAERLNATMMITRPHS 251
            |..||:.|.....|:..||.:.             ||..:.....|:.|:.  .|..:.:...|.
Mouse   446 VTVLEEPFVMVSENVLGKPKKY-------------QGFSIDVLDALSNYLG--FNYEIYVAPDHK 495

  Fly   252 YNN-------HNLSSDICFLEVAKEYVDVAMNIRFLVPDTFRKQAESTVSHTRDDLCVIVPKAKT 309
            |.:       :.|..::.|     :..|:.::...:.||. ....:.|..:....:.|::.:|:.
Mouse   496 YGSPQEDGTWNGLVGELVF-----KRADIGISALTITPDR-ENVVDFTTRYMDYSVGVLLRRAEK 554

  Fly   310 APTFWNIFRSFGSLVWALILVSVLVANVFCYILKSEVGRVPMQLFAGALT--------------- 359
            ....:.....|...:||.|..:||:..:..|:|.   ...|.:|..|::|
Mouse   555 TVDMFACLAPFDLSLWACIAGTVLLVGLLVYLLN---WLNPPRLQMGSMTSTTLYNSMWFVYGSF 616

  Fly   360 ------MPMTQIPPNHSIRLFLIFWLYFGLLICSAFKGNLTSMMVFQPYLPDINQLGALARS--- 415
                  :|.|.:    :.|:.:..|..|.|::.|::..||.:.:........|..|..|::.
Mouse   617 VQQGGEVPYTTL----ATRMMMGAWWLFALIVISSYTANLAAFLTITRIESSIQSLQDLSKQTDI 677

  Fly   416 HYHIIIRPRHVKHIQHFLTLGHKHESRI-------REQMLEVSDTQMYEMM-RNNDIRFAYLE-- 470
            .|..::.....:|:            |:       |:.|.    :||:.|: |:|......||
Mouse   678 PYGTVLDSAVYQHV------------RMKGLNPFERDSMY----SQMWRMINRSNGSENNVLESQ 726

  Fly   471 ------KYHIARFQVNSRV--HMHLGRP--LFHLMNSCLVPFHAVYIVPYGSPYLGFLDSLIRSS 525
                  ||....|..::.|  ::.:..|  .|:.:.:.:........:.:||||.......|...
Mouse   727 AGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIALQHGSPYRDVFSQRILEL 791

  Fly   526 HEFG-----FERYWDRIMNSAFIKSGVKVVNRRRGSGNDEPVVLKLQHFHAVFALWLVGIGMACI 585
            .:.|     ..::|.:........|    |:.::..|     .|.::....||.:...||.::|:
Mouse   792 QQSGDMDILKHKWWPKNGQCDLYSS----VDAKQKGG-----ALDIKSLAGVFCILAAGIVLSCL 847

  Fly   586 VLAWE 590
            :...|
Mouse   848 IAVLE 852

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
Grid2	NP_032193.1	Interaction with CBLN1 homotrimer. /evidence=ECO:0000250|UniProtKB:O43424	24..345
		Periplasmic_Binding_Protein_type1	28..429	CDD:385651
		PBP2_iGluR_delta_2	440..806	CDD:270449	70/403 (17%)
		Interaction with AP4M1. /evidence=ECO:0000250|UniProtKB:Q63226	921..991
		PDZ-binding	1005..1007

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846501
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740