Protein Alignment Ir85a and Gria2

DIOPT Version :10

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001344853.2
• Gene: Gria2 / 14800
• MGIID: 95809
• Length: 901
• Species: Mus musculus
• Alignment Length: 373
• Identity: 69/373 - (18%)
• Similarity: 129/373 - (34%)
• Gaps: 94/373 - (25%)

  Fly   272 DVAMNIRFLVPDTFRKQAESTVSHTRD----DLCVIVPK-AKTAPTFWNIFRSFGSLVWALILVS 331
            |:|     :.|.|.....|..:..::.    .:.:::.| .|:.|..::........:|..|:.:
Mouse   494 DIA-----IAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFA 553

  Fly   332 VLVANVFCYILK------------------------SEVGRVPMQLFA-GALTMPMTQIPPNH-S 370
            .:..:|..:::.                        :|.|......|: ||.......|.|.. |
Mouse   554 YIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMQQGCDISPRSLS 618

  Fly   371 IRLFLIFWLYFGLLICSAFKGNLTSMMVFQPYLPDINQLGALARSHYHIIIRPRHVKHIQHFLTL 435
            .|:....|.:|.|:|.|::..||.:.:..:..:..|.....|:          :..:.....|..
Mouse   619 GRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLS----------KQTEIAYGTLDS 673

  Fly   436 GHKHESRIREQMLEVSDTQMYEMMRNNDIR-FAYLEKYHIARFQVNSRVHMHLGRPLFHLMNSCL 499
            |...|. .|...:.|.| :|:..||:.:.. |.......:||.:.:...:.:|   |...||..:
Mouse   674 GSTKEF-FRRSKIAVFD-KMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYL---LESTMNEYI 733

  Fly   500 VPFHAVYIVPYGSPYLGFLD-----------SLIRSSHEFGFERYWDRIMNSAFIK---SGV--K 548
            ........:..|    |.||           |.:|:.            :|.|.:|   .||  |
Mouse   734 EQRKPCDTMKVG----GNLDSKGYGIATPKGSSLRTP------------VNLAVLKLSEQGVLDK 782

  Fly   549 VVNR---------RRGSGNDEPV-VLKLQHFHAVFALWLVGIGMACIV 586
            :.|:         .:.||:.|.. .|.|.:...||.:.:.|:|:|.:|
Mouse   783 LKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLV 830

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
Gria2	NP_001344853.2	PBP1_iGluR_AMPA_GluR2	28..398	CDD:380612
		PBP2_iGluR_AMPA	413..794	CDD:270433	58/335 (17%)