Protein Alignment CG8223 and nasp

DIOPT Version :9

• Sequence 1: NP_001246993.1
• Gene: CG8223 / 41045
• FlyBaseID: FBgn0037624
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_001164988.1
• Gene: nasp / 733514
• XenbaseID: XB-GENE-980254
• Length: 605
• Species: Xenopus tropicalis
• Alignment Length: 570
• Identity: 137/570 - (24%)
• Similarity: 224/570 - (39%)
• Gaps: 129/570 - (22%)

  Fly    23 VAVEPVAADTTPDNAPAVSTEGSGKAEQERAEKI-LKGKELFSQGSRNFLVKSYDEAADELSQVC 86
            :|.|..|..|..:.....||..|..||:.....| .:.|:|.:.|.::.::|....|.....:..
 Frog     1 MAEETAALSTGTEKTEDTSTAPSTSAEKADGMDIETEAKKLMATGQKHLVMKDVRSAVTSFQEAS 65

  Fly    87 QLYEEVYGELADELGQPLLLYAKALIAMALDENKVI-----DVPDEAADDDDED--------VDD 138
            .|..:.|||.|||.......|..:|:.:|..||.|:     .:|::..|.:.||        :|:
 Frog    66 SLLAKKYGETADECADAFYSYGMSLLELARMENGVLGNALEGMPEDEEDGEKEDPNIPSADNLDE 130

  Fly   139 DEEES---------AEDGAAKK-------------EEKKDTKEAANGASSSNG-KELDTIKEG-- 178
            .|.:.         |||..|.|             |..::|.|........|| .|.:.:.:|
 Frog   131 KERDQLREQVYNAMAEDERASKSTSESEGKGKPEDESNRETDEKNKPVEKMNGDMETEDVTDGLK 195

  Fly   179 SDEA------DSTGEAEQAQSDEKP-------SKKVPTGVDEVSSS-----------------NG 213
            :|.|      |.:|:||.|:..|.|       :.:..|..:::|.|                 |.
 Frog   196 ADSATQDVTMDESGKAEAAKGAETPGEHTEKENSEAETQKEKISESKENESKDQEKTDAKEIANQ 260

  Fly   214 GGGAAVNDDERPSTS-----NGEVTASCSNGAAPAVEEEP-----------EEEEGVS------- 255
            ...:....:||..|.     :.||:|......:...|.|.           |||||..
 Frog   261 SPDSTEVTEERTHTDTSEKMDSEVSAETEEPKSIPTENEASKPDDKEKMEGEEEEGEDSEENDEG 325

  Fly   256 -----------------GSLQLAWEILEAAAQIFSR-QGLSGLPYLAEVQTELANIEFENGILEA 302
                             |:||||||:|:....||.| |........|:...:|..:..|:.....
 Frog   326 TEENEGTEEKETEEEDVGNLQLAWEMLDLCKLIFKRQQSKEAQLKAAQAHLKLGEVSVESENYSQ 390

  Fly   303 AREDYEKALKIHGELPTRNRRALAELHYKIGLTYLMQQLNKEGATALRQSSVLIEEEIAEIKGKD 367
            |.||:...|.|..|....:.|.|||.:|.:||.|.....:::..:...||..:||:.:..:..:.
 Frog   391 AVEDFLACLNIQKEHLEEHDRLLAETNYHLGLAYQYSSKHEDAISHFTQSVGVIEKRMGVLTKQL 455

  Fly   368 EPS--ERD--RNNMLDLEETKQEILAKIQEIEEMQAQTIAEVRAALDSYIKPMSSGDAAAASSSS 428
            |.|  |.|  :..|.:|::...:|..||::.:|.|....|...|..::.:          ..||.
 Frog   456 ETSVGEPDEVKKEMDELKDLLPDIKEKIEDSKEAQKNATATEIALKETLV----------GGSSG 510

  Fly   429 SSSANGAASSSSSSSKGAAAASSSTISSSSAKPTDITHLI-KRKKPEDPS 477
            .|..||:.|:||::   ...:..||:..::. .:||:||: |::|||:.|
 Frog   511 FSQENGSTSASSTT---VEKSGDSTVPVTNC-VSDISHLVRKKRKPEEES 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8223	NP_001246993.1	TPR_12	281..352	CDD:290160	17/70 (24%)
		TPR repeat	283..313	CDD:276809	7/29 (24%)
		TPR repeat	326..351	CDD:276809	6/24 (25%)
nasp	NP_001164988.1	TPR_12	371..446	CDD:290160	20/74 (27%)
		TPR repeat	371..401	CDD:276809	7/29 (24%)
		SHNi-TPR	372..409	CDD:287487	9/36 (25%)
		TPR repeat	414..439	CDD:276809	6/24 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I4775
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1176629at2759
OrthoFinder	1	1.000	-	-		FOG0005069
OrthoInspector	1	1.000	-	-		oto102976
Panther	1	1.100	-	-	LDO	PTHR15081
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.160