DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment M1BP and DOT5

DIOPT Version :9

Sequence 1:	NP_649825.1	Gene:	M1BP / 41042	FlyBaseID:	FBgn0037621	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_172787.1	Gene:	DOT5 / 837889	AraportID:	AT1G13290	Length:	302	Species:	Arabidopsis thaliana

Alignment Length:	302	Identity:	61/302 - (20%)
Similarity:	93/302 - (30%)	Gaps:	119/302 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 NDAYVYDSDDEVAVLD------------------NVLDDEYEH-----ENIVVKKCSLPPKPKVR 238
            |:.|.:..|::..||.                  ...|.|:.|     ..:.|.....||.
plant     4 NNQYSFSGDEDSVVLSLGPPGQQYPSHNKPTSTKPSSDHEFNHPLTNPNGVTVALHIGPPS---- 64

  Fly   239 SDDARRRGTGGVYICEQCGNHIKGRMAFELHCRRHR-----------GDKQFGCELCQSRFCTTS 292
            ||.....|          ||:.:|     |..|:.:           |..||.|.:|...|...:
plant    65 SDKETLSG----------GNNQEG-----LTARQGQYWIPSLSQILVGPTQFSCSVCNKTFNRFN 114

  Fly   293 ELKRHMRKHTGE---RPFACK-------------YCGRCFTDYTTRVKHERTHTNERPYVCGTCG 341
            .::.||..|..:   .|.:.:             ||  |.......:.|.|:    :|.
plant   115 NMQMHMWGHGSQYRKGPESLRGTKSSSSILRLPCYC--CAEGCKNNIDHPRS----KPL------ 167

  Fly   342 KAFTTGYILKNHMLIHSGERAYRC-ELCDKSFMLPTHLSTH---------------FRSGVHKR- 389
            |.|.|   |:.|.....|.:.:|| :.|:|:|.:.....||               |:   |||
plant   168 KDFRT---LQTHYKRKHGAKPFRCRKKCEKTFAVRGDWRTHEKNCGKLWFCVCGSDFK---HKRS 226

  Fly   390 -----------HLEKAEMKQVL----EQEQKRELKEEEEDSL 416
                       |.......:|:    ..|...|.:|||||.:
plant   227 LKDHVRAFGDGHAAHTVSDRVVGIGDADEDDEEEEEEEEDDV 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
M1BP	NP_649825.1	zf-AD	13..84	CDD:214871
		C2H2 Zn finger	253..273	CDD:275368	5/19 (26%)
		COG5048	276..>331	CDD:227381	14/70 (20%)
		C2H2 Zn finger	281..301	CDD:275368	5/19 (26%)
		zf-H2C2_2	293..317	CDD:290200	7/39 (18%)
		C2H2 Zn finger	309..329	CDD:275368	5/32 (16%)
		zf-H2C2_2	324..346	CDD:290200	5/21 (24%)
		C2H2 Zn finger	337..357	CDD:275368	5/19 (26%)
		zf-H2C2_2	350..372	CDD:290200	7/22 (32%)
		C2H2 Zn finger	365..383	CDD:275368	6/33 (18%)
DOT5	NP_172787.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050