DRSC/TRiP Functional Genomics Resources

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Protein Alignment M1BP and ZNF221

DIOPT Version :9

Sequence 1:NP_649825.1 Gene:M1BP / 41042 FlyBaseID:FBgn0037621 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_001284517.1 Gene:ZNF221 / 7638 HGNCID:13014 Length:617 Species:Homo sapiens


Alignment Length:221 Identity:64/221 - (28%)
Similarity:89/221 - (40%) Gaps:60/221 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   253 CEQCGNHIKGRMAFELHCRRHRGDKQFGCELCQSRFCTTSELKRHMRKHTGERPFACKYCGR--- 314
            |.|||.....|.|..:||:.|.|:|.:.||.|...|...|:|:.|.|.||||:||.|..||:   
Human   256 CGQCGKGFHSRSALNVHCKLHTGEKPYNCEECGKAFIHDSQLQEHQRIHTGEKPFKCDICGKSFR 320

  Fly   315 ----------------------CFTDYTTR-------------------------------VKHE 326
                                  |..::..|                               .||:
Human   321 VRSRLNRHSMVHTGEKPFRCDTCGKNFRQRSALNSHSMVHIEEKPYKCEQCGKGFICRRDFCKHQ 385

  Fly   327 RTHTNERPYVCGTCGKAFTTGYILKNHMLIHSGERAYRCELCDKSFMLPTHLSTHFRSGVHKRHL 391
            ..||.|:||.|..|||.|.....|.||..:|||:::::||.|.|.|...:..|:|.||    .:.
Human   386 MVHTGEKPYNCKECGKTFRWSSCLLNHQQVHSGQKSFKCEECGKGFYTNSRRSSHQRS----HNG 446

  Fly   392 EKAEMKQVLEQEQKRELKEEEEDSLH 417
            ||....:...::.||.|..|....:|
Human   447 EKPYNCEECGKDYKRRLDLEFHQRVH 472

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
M1BPNP_649825.1 zf-AD 13..84 CDD:214871
C2H2 Zn finger 253..273 CDD:275368 8/19 (42%)
COG5048 276..>331 CDD:227381 23/110 (21%)
C2H2 Zn finger 281..301 CDD:275368 8/19 (42%)
zf-H2C2_2 293..317 CDD:290200 13/48 (27%)
C2H2 Zn finger 309..329 CDD:275368 7/75 (9%)
zf-H2C2_2 324..346 CDD:290200 12/21 (57%)
C2H2 Zn finger 337..357 CDD:275368 8/19 (42%)
zf-H2C2_2 350..372 CDD:290200 10/21 (48%)
C2H2 Zn finger 365..383 CDD:275368 7/17 (41%)
ZNF221NP_001284517.1 KRAB 30..70 CDD:307490
COG5048 166..576 CDD:227381 64/221 (29%)
C2H2 Zn finger 172..192 CDD:275368
C2H2 Zn finger 200..220 CDD:275368
C2H2 Zn finger 228..248 CDD:275368
C2H2 Zn finger 256..276 CDD:275368 8/19 (42%)
C2H2 Zn finger 284..304 CDD:275368 8/19 (42%)
C2H2 Zn finger 312..332 CDD:275368 3/19 (16%)
C2H2 Zn finger 340..360 CDD:275368 2/19 (11%)
C2H2 Zn finger 368..388 CDD:275368 2/19 (11%)
C2H2 Zn finger 396..416 CDD:275368 8/19 (42%)
C2H2 Zn finger 424..444 CDD:275368 9/23 (39%)
C2H2 Zn finger 452..472 CDD:275368 4/19 (21%)
C2H2 Zn finger 480..500 CDD:275368
C2H2 Zn finger 508..528 CDD:275368
C2H2 Zn finger 536..556 CDD:275368
C2H2 Zn finger 564..584 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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