DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment M1BP and CG4854

DIOPT Version :9

Sequence 1:	NP_649825.1	Gene:	M1BP / 41042	FlyBaseID:	FBgn0037621	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster

Alignment Length:	387	Identity:	111/387 - (28%)
Similarity:	169/387 - (43%)	Gaps:	88/387 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CRVCAKYASNKRSPKLFERSNTKMI-------DNIEALTGLRLENYGCLPDQICECCSMELASAV 70
            ||:|           |.:..:..::       |.|:..||:.|......|::||..|::.|.:|:
  Fly    12 CRIC-----------LVQPKDESLMPTEPDFPDKIKRCTGVELSESPDWPNRICTSCALLLRAAL 65

  Fly    71 KLRERCIAAQRELLLGLTEEQRQGISAFYRAAVMGEDIVQTVKTPDDDEVYATYQEIVLEEPKEE 135
            |||..|...:::|     :||:                               .|||.:|...:|
  Fly    66 KLRSLCQQTEKDL-----KEQK-------------------------------LQEINIEIVHDE 94

  Fly   136 IDDTKVEYDNTYYEVAEGHAGEDDAASLIEEADYDSIMAEDEEQQQTLELDEDTELIVGDVNDAY 200
             .:||.:.::.  ::::..|...|:     |.:|:.:.:.|    .|||..||
  Fly    95 -QETKKKTESR--DLSKNEATGSDS-----ELEYEYLDSYD----VTLESSED------------ 135

  Fly   201 VYDSDDEVAVLDNVLDDEYEHENIVVKKCSLPPKPKVRSDDARRRGTGGVYICEQCGNHIKGRMA 265
            |..|.||:..::..:....|      ...||.|||....|:  ..|....:.|..|.|....|:.
  Fly   136 VACSADELVSIEPAISAPEE------SVYSLSPKPVTFEDE--DSGQAASFTCNICNNVYSERVK 192

  Fly   266 FELHCRRHRGDKQFGCELCQSRFCTTSELKRHMRKHTGERPFACKYCGRCFTDYTTRVKHERTHT 330
            ...|.:.|...|...||:|..||..|.:|.|||..|||.||:.|.||...|.|.:||:||:|.||
  Fly   193 LTNHMKVHSAKKPHECEICHKRFRQTPQLARHMNTHTGNRPYKCDYCDSRFADPSTRIKHQRIHT 257

  Fly   331 NERPYVCGTCGKAFTTGYILKNHMLIHSGERAYRCELCDKSFMLPTHLSTHFRSGVHKRHLE 392
            |||||.|..|.::|....:|:.|:..|:|||.:.|:.|.|||....|.::|.:|  |||..|
  Fly   258 NERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFSQLHHKNSHEKS--HKRTKE 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
M1BP	NP_649825.1	zf-AD	13..84	CDD:214871	19/77 (25%)
		C2H2 Zn finger	253..273	CDD:275368	5/19 (26%)
		COG5048	276..>331	CDD:227381	27/54 (50%)
		C2H2 Zn finger	281..301	CDD:275368	10/19 (53%)
		zf-H2C2_2	293..317	CDD:290200	12/23 (52%)
		C2H2 Zn finger	309..329	CDD:275368	10/19 (53%)
		zf-H2C2_2	324..346	CDD:290200	13/21 (62%)
		C2H2 Zn finger	337..357	CDD:275368	5/19 (26%)
		zf-H2C2_2	350..372	CDD:290200	9/21 (43%)
		C2H2 Zn finger	365..383	CDD:275368	7/17 (41%)
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071	12/55 (22%)
		C2H2 Zn finger	180..200	CDD:275368	5/19 (26%)
		zf-H2C2_2	193..217	CDD:290200	8/23 (35%)
		COG5048	201..>258	CDD:227381	27/56 (48%)
		C2H2 Zn finger	208..228	CDD:275368	10/19 (53%)
		zf-H2C2_2	221..244	CDD:290200	12/22 (55%)
		C2H2 Zn finger	236..256	CDD:275368	10/19 (53%)
		zf-H2C2_2	251..273	CDD:290200	13/21 (62%)
		C2H2 Zn finger	264..284	CDD:275368	5/19 (26%)
		zf-H2C2_2	277..301	CDD:290200	11/23 (48%)
		C2H2 Zn finger	292..312	CDD:275368	8/21 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960