DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment M1BP and CG6813

DIOPT Version :9

Sequence 1:	NP_649825.1	Gene:	M1BP / 41042	FlyBaseID:	FBgn0037621	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster

Alignment Length:	390	Identity:	106/390 - (27%)
Similarity:	150/390 - (38%)	Gaps:	118/390 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CRVCAKYASNKRSP-KLFERSNTKMIDNIEALTGLRLENYGCLPDQICECCSMELASAVKLRERC 76
            ||:|    |...:| .||...|..::..|.::||:.|.....:..|:|..|...|.:|:|.|:||
  Fly     6 CRIC----SRSDAPIDLFGPGNGHLVRQIHSITGVELSCKKEISGQMCTTCLDNLQAAIKFRQRC 66

  Fly    77 IAAQRELLLGLTEEQRQGISAFYRAAVMGEDIVQTVKTPDDDEVYATYQEIVLEEPKEEIDDTKV 141
            |.|:::.|                                                      .::
  Fly    67 IIAEKQNL------------------------------------------------------ERI 77

  Fly   142 EYDNTYYEVAEGHAGEDDAASLIEEADYDSIMAED-EEQQQTLELDEDTELIVGDVNDAYVYDSD 205
            |.|:                   ::...|.|:.|| ::.|...||||
  Fly    78 ECDS-------------------KDCSTDPIIYEDIDDNQIESELDE------------------ 105

  Fly   206 DEVAVLDNVLDDEYEHENIVVKKCSLPPKPKVRSDDARRR-----GTGGVYICEQCGNHIKGRMA 265
                   ::|..|       ||...:|...||.:..:...     |..|.|:|..||..|..:..
  Fly   106 -------SILCPE-------VKDLPMPSAEKVSAPTSLNHQKSIGGGTGPYVCPDCGRIINNKSN 156

  Fly   266 FELHCRRHRGDKQFGCEL--CQSRFCTTSELKRHMRKHTGERPFACKYCGRCFTDYTTRVKHERT 328
            |:.|..||.|.|.|.|..  |:..|.|..||..|.|.||||:|:.|.||.|.|:....|.:|.|.
  Fly   157 FQEHTLRHTGIKNFHCVFLNCERSFATRKELTSHTRIHTGEQPYVCVYCPRRFSSSGARQEHHRR 221

  Fly   329 HTNERPYVCGTCGKAFTTGYILKNHMLIHSGERAYRCELCDKSFMLPTHLSTHFRSGVHKRHLEK 393
            |.|||.|.|.||.|:|.:...|:.|.:||...|.:.|.:|.|.|...:||.||..|.:|||..||
  Fly   222 HRNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKRISHLMTHLSSNIHKRKEEK 286

Fly 394 393
Fly 287 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
M1BP	NP_649825.1	zf-AD	13..84	CDD:214871	23/71 (32%)
		C2H2 Zn finger	253..273	CDD:275368	6/19 (32%)
		COG5048	276..>331	CDD:227381	24/56 (43%)
		C2H2 Zn finger	281..301	CDD:275368	8/21 (38%)
		zf-H2C2_2	293..317	CDD:290200	13/23 (57%)
		C2H2 Zn finger	309..329	CDD:275368	8/19 (42%)
		zf-H2C2_2	324..346	CDD:290200	12/21 (57%)
		C2H2 Zn finger	337..357	CDD:275368	7/19 (37%)
		zf-H2C2_2	350..372	CDD:290200	8/21 (38%)
		C2H2 Zn finger	365..383	CDD:275368	8/17 (47%)
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071	24/127 (19%)
		C2H2 Zn finger	144..164	CDD:275368	6/19 (32%)
		C2H2 Zn finger	172..194	CDD:275368	8/21 (38%)
		zf-H2C2_2	186..211	CDD:290200	14/24 (58%)
		UFD2	<256..>294	CDD:227443	14/31 (45%)
		C2H2 Zn finger	258..280	CDD:275368	9/21 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.060