DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment M1BP and CG6808

DIOPT Version :9

Sequence 1:	NP_649825.1	Gene:	M1BP / 41042	FlyBaseID:	FBgn0037621	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001247055.1	Gene:	CG6808 / 41394	FlyBaseID:	FBgn0037921	Length:	375	Species:	Drosophila melanogaster

Alignment Length:	414	Identity:	117/414 - (28%)
Similarity:	174/414 - (42%)	Gaps:	69/414 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 STCRVCAKYASNKRSPKLFERSNTKMIDNIEALTGLRLENYGCLPDQICECCSMELASAVKLRER 75
            |.||.|.|..:......|||.:..|:   :.:..|..::....||||||..|.|:|....:....
  Fly     8 SMCRTCRKKGTQSTLQSLFESNAHKL---LISYAGTSVKPDDGLPDQICTVCLMQLEEVDRFLSA 69

  Fly    76 CIAAQRELLLGLTEEQRQGISAFYRAAVMGEDIVQTVKTPDDDEVYATYQEIVLEEP----KEEI 136
            |..:... |..|..:.....|||           :|::..|.           ||:.    |:.|
  Fly    70 CKQSDAH-LRSLVRQTLSSASAF-----------ETLEDKDQ-----------LEQKKRARKQNI 111

  Fly   137 DDTKVEYDNTYYEVAEG--HAGEDDAASLIEEADYD-----SIMAEDEE---QQQTLELDEDTEL 191
            ....:|.:...::..|.  ...:||....|.:...|     ::.||:|:   |:.....|.|.:.
  Fly   112 SGRLIEENPINFKTQENALETTKDDEILPINKFSSDFVFDLNVNAENEKDIHQEDYTISDMDLDR 176

  Fly   192 IVGDVNDAYVYDSDDEVAVLDNVLDDEYEHENI------VVK---KCSLPPKPKVRSDDARRRGT 247
            .:.|.|.:..| |.:..|..|::.:...::.|:      |:.   .|. |.|
  Fly   177 EISDQNYSETY-SQESSAATDSIQETSEDYHNLEPSADYVIDLGVACE-PDK------------- 226

  Fly   248 GGVYICEQCGNHIKGRMAFELHCRRHRGDKQFGCELCQSRFCTTSELKRHMRKHTGERPFACKYC 312
               |.|:.|.|..:.......|.:.||.:|...||:||..|.....||.|||.||||:|:.|.||
  Fly   227 ---YRCKICSNTYRCLSQLNAHSQVHRKEKDHQCEVCQKTFRAACNLKTHMRTHTGEKPYQCCYC 288

  Fly   313 GRCFTDYTTRVKHERTHTNERPYVCGTCGKAFTTGYILKNHMLIHSGERAYRCELCDKSFMLPTH 377
            .|.|.|.:|..||||.|||||||.|..|||.|:.......|..:||.|::::|.:|.|.|.|...
  Fly   289 SRRFADNSTHRKHERLHTNERPYACNICGKTFSLSSSRNAHYYLHSSEKSHKCLMCKKEFRLKHQ 353

  Fly   378 LSTHFRSGVHKRHLEKAEMKQVLE 401
            |:.|.:|..|:  |...|...|:|
  Fly   354 LTAHEKSLAHR--LIAKEYSDVVE 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
M1BP	NP_649825.1	zf-AD	13..84	CDD:214871	19/70 (27%)
		C2H2 Zn finger	253..273	CDD:275368	4/19 (21%)
		COG5048	276..>331	CDD:227381	28/54 (52%)
		C2H2 Zn finger	281..301	CDD:275368	10/19 (53%)
		zf-H2C2_2	293..317	CDD:290200	14/23 (61%)
		C2H2 Zn finger	309..329	CDD:275368	11/19 (58%)
		zf-H2C2_2	324..346	CDD:290200	16/21 (76%)
		C2H2 Zn finger	337..357	CDD:275368	6/19 (32%)
		zf-H2C2_2	350..372	CDD:290200	7/21 (33%)
		C2H2 Zn finger	365..383	CDD:275368	7/17 (41%)
CG6808	NP_001247055.1	zf-AD	9..79	CDD:214871	20/73 (27%)
		C2H2 Zn finger	229..249	CDD:275368	4/19 (21%)
		zf-C2H2	255..277	CDD:278523	10/21 (48%)
		C2H2 Zn finger	257..277	CDD:275368	10/19 (53%)
		zf-H2C2_2	269..293	CDD:290200	14/23 (61%)
		C2H2 Zn finger	285..305	CDD:275368	11/19 (58%)
		zf-H2C2_2	299..321	CDD:290200	15/21 (71%)
		C2H2 Zn finger	313..333	CDD:275368	6/19 (32%)
		C2H2 Zn finger	341..359	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I3338
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960