DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment M1BP and ranshi

DIOPT Version :9

Sequence 1:	NP_649825.1	Gene:	M1BP / 41042	FlyBaseID:	FBgn0037621	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster

Alignment Length:	387	Identity:	154/387 - (39%)
Similarity:	219/387 - (56%)	Gaps:	56/387 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CRVCAKYASNKRSPKLFERSNTKMIDNIEALTGLRLENYGCLPDQICECCSMELASAVKLRERCI 77
            ||.|.|..:.:||..:||:.|...:::|:.|||..|:|...||:::|..|...|..|:..||||:
  Fly     6 CRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRERCL 70

  Fly    78 AAQRELLLGLTEEQRQGISAFYRAAVMGEDIVQTVKTPDDDEVYATYQEIVLEEPKEEIDDTKVE 142
            ..|||||                            .:.||::    :..|..|.||..::..::|
  Fly    71 EVQRELL----------------------------HSQDDED----FLRICQESPKSVLEQEELE 103

  Fly   143 YDNTYYEVAEGHAGEDDAASLIEEADYDSIMAEDEEQQQTLELDEDTELIVGDVN----DAYVYD 203
            .|.....:      |.:....:.|....|...:.|:.....:::||......|::    |..:|:
  Fly   104 LDLAEISI------EVERLDDLNEGPIQSSGFKVEDILNESKINEDEPNNEDDIDYSEMDYLIYE 162

  Fly   204 SDDEVAVLDNVLDDEYEHENIVVKKCSLPPKPKVRSDDARRRGTGGVYICEQCGNHIKGRMAFEL 268
            ||.||.....:..|.   ||           ||.|.:....|.:...:.||:||||||.|::|.|
  Fly   163 SDTEVDAKQELKSDS---EN-----------PKKRRNRRNPRDSNRTFFCEECGNHIKDRISFIL 213

  Fly   269 HCRRHRGDKQFGCELCQSRFCTTSELKRHMRKHTGERPFACKYCGRCFTDYTTRVKHERTHTNER 333
            ||:||||.|:||||.|:.||||.:|||||:||||||:||.|::|.|.|:||:||:||||||||||
  Fly   214 HCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNER 278

  Fly   334 PYVCGTCGKAFTTGYILKNHMLIHSGERAYRCELCDKSFMLPTHLSTHFRSGVHKRHLEKAE 395
            |:||..|..||||.||||||||:|:||:|:||:||||.|...|||:||:||..|:|:::||:
  Fly   279 PFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYRSNAHRRNMQKAD 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
M1BP	NP_649825.1	zf-AD	13..84	CDD:214871	28/70 (40%)
		C2H2 Zn finger	253..273	CDD:275368	13/19 (68%)
		COG5048	276..>331	CDD:227381	37/54 (69%)
		C2H2 Zn finger	281..301	CDD:275368	13/19 (68%)
		zf-H2C2_2	293..317	CDD:290200	16/23 (70%)
		C2H2 Zn finger	309..329	CDD:275368	12/19 (63%)
		zf-H2C2_2	324..346	CDD:290200	16/21 (76%)
		C2H2 Zn finger	337..357	CDD:275368	14/19 (74%)
		zf-H2C2_2	350..372	CDD:290200	16/21 (76%)
		C2H2 Zn finger	365..383	CDD:275368	11/17 (65%)
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	28/70 (40%)
		C2H2 Zn finger	198..218	CDD:275368	13/19 (68%)
		COG5048	222..>276	CDD:227381	37/53 (70%)
		C2H2 Zn finger	226..246	CDD:275368	13/19 (68%)
		zf-H2C2_2	238..262	CDD:290200	16/23 (70%)
		C2H2 Zn finger	254..274	CDD:275368	12/19 (63%)
		zf-H2C2_2	269..291	CDD:290200	16/21 (76%)
		C2H2 Zn finger	282..302	CDD:275368	14/19 (74%)
		zf-H2C2_2	295..319	CDD:290200	17/23 (74%)
		C2H2 Zn finger	310..328	CDD:275368	11/17 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447746
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26093
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	1	1.100	-	-	P	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.900