DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment M1BP and Zif

DIOPT Version :9

Sequence 1:NP_649825.1 Gene:M1BP / 41042 FlyBaseID:FBgn0037621 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_001189188.1 Gene:Zif / 40795 FlyBaseID:FBgn0037446 Length:388 Species:Drosophila melanogaster


Alignment Length:431 Identity:120/431 - (27%)
Similarity:190/431 - (44%) Gaps:88/431 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 TCRVCAKYASNKRSPKL------FERSNTKMIDNIEALTGLRLENYGCLPDQICECCSMELASAV 70
            |||||  .|.::|..:|      .|.|..:|:..:..::...|.:...:||.||:.|.:||..|.
  Fly     9 TCRVC--LAQSERLQRLDEIREEGEESPNEMLIQLLGVSYSNLNDREHIPDGICKSCKVELNMAY 71

  Fly    71 KLRERCIAAQREL-----LLGLTEEQRQGISAFYRAAVMGEDIVQTVKTPDDDEVYATYQEIVLE 130
            :.||:.:..|.|:     .|||.:|               .|::..                   
  Fly    72 QFREKALRKQMEIEEYCRELGLLDE---------------SDVMMI------------------- 102

  Fly   131 EPKEEIDDTKVEYDNTYYEVAEGHAGEDDAASLIEEADYDSIMAEDEEQQQTLELD-EDTELIVG 194
              ||| |.::.:.|...|.:.|...||::             ..|::..::.||:| .|.:..:|
  Fly   103 --KEE-DGSQQQCDEEMYILEETTTGEEE-------------HQEEKGHEEYLEVDTSDQQECIG 151

  Fly   195 D----VNDAYVYD-SDDEVAVLDNVLDDEYEHENIVVKKCSLPPKPKVRSDDAR---RRGTG--- 248
            |    :.|.|..: :.|:..:   ||:.|.::|....::.:|....|......|   |||..   
  Fly   152 DTIEYLEDNYTIEMNSDQTEI---VLESEKQYEETPSQQLALQEAAKASLKARRGRVRRGLNSLT 213

  Fly   249 -------GVYICEQCGNHIKGRMAFELHCRRHRGDKQFGCELCQSRFCTTSELKRHMRKHTGERP 306
                   |.|||:.|||..:.|.....|.|||.|..|:.||||.::|....:|::||..|||.:|
  Fly   214 TSDGTEKGGYICDVCGNFYEKRGRMMEHRRRHDGICQYACELCDAKFQVREQLRKHMYSHTGSKP 278

  Fly   307 FACKYCGRCFTDYTTRVKHERTHTNERPYVCGTCGKAFTTGYILKNHMLIHSGERAYRCELCDKS 371
            :.|.:|.|.|...:....||..|...:||||..|.|||...:.|..|.||||..:.|||:.|:|.
  Fly   279 YKCSFCSRQFFYESVLKSHENVHRGIKPYVCKVCDKAFAYAHSLTKHELIHSDIKLYRCDYCNKD 343

  Fly   372 FMLPTHLSTHFRSGVHKRHL---EKAEMKQVLEQEQKRELK 409
            |.|..|:..|..:.:|:..:   |..:::.|.||....|::
  Fly   344 FRLLHHMRQHEETKLHQNAVMLAESMKVEMVAEQGGGNEIR 384

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
M1BPNP_649825.1 zf-AD 13..84 CDD:214871 23/81 (28%)
C2H2 Zn finger 253..273 CDD:275368 7/19 (37%)
COG5048 276..>331 CDD:227381 20/54 (37%)
C2H2 Zn finger 281..301 CDD:275368 8/19 (42%)
zf-H2C2_2 293..317 CDD:290200 10/23 (43%)
C2H2 Zn finger 309..329 CDD:275368 6/19 (32%)
zf-H2C2_2 324..346 CDD:290200 11/21 (52%)
C2H2 Zn finger 337..357 CDD:275368 8/19 (42%)
zf-H2C2_2 350..372 CDD:290200 11/21 (52%)
C2H2 Zn finger 365..383 CDD:275368 7/17 (41%)
ZifNP_001189188.1 zf-AD 9..87 CDD:285071 24/79 (30%)
C2H2 Zn finger 225..245 CDD:275368 7/19 (37%)
COG5048 <250..369 CDD:227381 45/118 (38%)
C2H2 Zn finger 253..273 CDD:275368 8/19 (42%)
zf-H2C2_2 266..288 CDD:290200 10/21 (48%)
C2H2 Zn finger 281..301 CDD:275368 6/19 (32%)
zf-H2C2_2 294..318 CDD:290200 11/23 (48%)
C2H2 Zn finger 309..329 CDD:275368 8/19 (42%)
C2H2 Zn finger 337..353 CDD:275368 6/15 (40%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 62 1.000 Inparanoid score I2531
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.960

Return to query results.
Submit another query.