DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment M1BP and CG14667

DIOPT Version :9

Sequence 1:	NP_649825.1	Gene:	M1BP / 41042	FlyBaseID:	FBgn0037621	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster

Alignment Length:	389	Identity:	102/389 - (26%)
Similarity:	158/389 - (40%)	Gaps:	76/389 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 HLKSTCRVCA-KYASNKRSPKLFERSNTKMIDNIEALTGLRLENYGCLPDQICECCSMELASAVK 71
            :|...||:|| |...::|...:|.....|.:..::.:||:.|.....||:.:||.|..||..|.|
  Fly     2 NLADVCRICANKIMGHQRDRNIFIHMRGKYLGQLKLITGVELTRNQGLPEIVCERCFSELDLATK 66

  Fly    72 LRERCIAAQRELLLGLTEEQRQGISAFYRAAVMGEDIVQTVKTPDDDEVYATYQEIVLEEPKEEI 136
            .|||||.:|:.||                      ||::  ||.|...|:.......|:|...:.
  Fly    67 FRERCIFSQKYLL----------------------DIIK--KTSDQSTVHVELSSEPLDEQLIDA 107

  Fly   137 DDTKVEYDNTYYEVAEGHAGEDDAASLIEEADYDSIMAEDEEQQQTLELDEDTELIVGDVNDAYV 201
            |..:..||:..|...:|                   ..|:.:..:.:|||:|....|....:|..
  Fly   108 DQLETHYDDDQYVCYQG-------------------TKEEHQDLEEIELDDDPSAAVIAAAEAAA 153

  Fly   202 YDSDDEVAVLDNVLDDEYEHENIVVKKCSLPPKPKVRSDDARRRGTGGVYICEQCGNHIKGRMAF 266
                 |.|..:::.:.|.|..                   |:||  ...:||::||........:
  Fly   154 -----EAAQQEDLQEQEMERA-------------------AKRR--SNFFICDECGTLFHDAFLY 192

  Fly   267 ELHCRRHRGDKQ----FGCELCQSRFCTTSELKRHMRK-HTGERPFACKYCGRCFTDYTTRVKHE 326
            ..|...|:..:.    |.|..|...|...:.||:|..: |...|.|.|..|...|.....:::|:
  Fly   193 TEHLNGHQNRRDMNQFFPCPECPQTFNKKALLKQHRTQVHLINRRFQCTICHEAFASLGAKLRHD 257

  Fly   327 RTHTNERPYVCGTCGKAFTTGYILKNHMLIHSGE-RAYRCELCDKSFMLPTHLSTHFRSGVHKR 389
            :.|.|||||.|..||..|::...|:||...||.: |.:|||.|:..|:....|..|.::..|||
  Fly   258 KAHKNERPYPCLECGMIFSSVSELQNHFSTHSKQIRKFRCEPCNMDFITRRGLVAHTKTAPHKR 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
M1BP	NP_649825.1	zf-AD	13..84	CDD:214871	26/71 (37%)
		C2H2 Zn finger	253..273	CDD:275368	4/19 (21%)
		COG5048	276..>331	CDD:227381	15/59 (25%)
		C2H2 Zn finger	281..301	CDD:275368	6/20 (30%)
		zf-H2C2_2	293..317	CDD:290200	8/24 (33%)
		C2H2 Zn finger	309..329	CDD:275368	4/19 (21%)
		zf-H2C2_2	324..346	CDD:290200	11/21 (52%)
		C2H2 Zn finger	337..357	CDD:275368	7/19 (37%)
		zf-H2C2_2	350..372	CDD:290200	10/22 (45%)
		C2H2 Zn finger	365..383	CDD:275368	6/17 (35%)
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	28/95 (29%)
		C2H2 Zn finger	179..199	CDD:275368	4/19 (21%)
		C2H2 Zn finger	211..232	CDD:275368	6/20 (30%)
		C2H2 Zn finger	240..260	CDD:275368	4/19 (21%)
		zf-C2H2_8	243..313	CDD:292531	25/69 (36%)
		C2H2 Zn finger	268..288	CDD:275368	7/19 (37%)
		C2H2 Zn finger	297..316	CDD:275368	6/18 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.960