DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment M1BP and D19B

DIOPT Version :9

Sequence 1:NP_649825.1 Gene:M1BP / 41042 FlyBaseID:FBgn0037621 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_477297.1 Gene:D19B / 38717 FlyBaseID:FBgn0022699 Length:774 Species:Drosophila melanogaster


Alignment Length:549 Identity:108/549 - (19%)
Similarity:190/549 - (34%) Gaps:183/549 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MSKSALKHLKSTCRVCAKYASNKRSPKLFERSNTKMIDNIEALTGLRLENYGCLPDQICECCSME 65
            |::.:...:.:.||.|.....:..:..||....  :...:...|.|.:|.....|..:|..|..:
  Fly     1 MNEESQYSIHTVCRTCLSTVDDSAAYDLFRVPG--LAKKLCVCTSLSVEQADGFPKNLCNVCFSK 63

  Fly    66 LASAVKLRERCIAAQRELLLGLTEEQRQGISAFYRAAVMGEDIVQT----VKTPDDDEVYATYQ- 125
            |......:::|:.:.::.      :.....:||  |.....|::.|    ...|.::|....:. 
  Fly    64 LNDLHDFQKQCVDSVQKF------QDLVASNAF--ACQTNFDVLDTSAAVADLPGEEEDNVHFDP 120

  Fly   126 ------EIV---------LEEPKEEIDDTKVEYDNTYYEVAEGHAGEDDAASLIEEADYDS---I 172
                  ||:         ||..::|:::.::|.:..:     |...:||:.....:.|.|:   |
  Fly   121 LLNSKIEIIENEEDVFKMLESVEKEVEEVEMEMEQPF-----GRVSQDDSFESGNDNDLDADFQI 180

  Fly   173 MAEDE------------------------EQQQTLELDEDTELIVGDVNDAYVYDSD-------- 205
            .::|:                        .::|..|.:|..|....|.:|....|..        
  Fly   181 SSDDDIPLAQRSRRGATRGSKAKGKPKSAAKRQEEESEESEETSSSDDSDGNPKDKPKRKRIPAT 245

  Fly   206 --DEVAVLD-NVLDDEYE-----------HENIVVKKCSLPPKPKVRSDDARRRG---------- 246
              |...::| ::...:::           |.:::..:|::         ::.|:|          
  Fly   246 ERDRHRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTV---------ESCRKGFTTANGLRVH 301

  Fly   247 -------TGGVYIC--EQCGNHIKGRMAFELHCRR-HRGD---KQFGCELCQSRFCTTSELKRHM 298
                   |..::.|  |.|.......:....|.:| |:.|   :.|.|..|:..|...:.||:||
  Fly   302 VEHAHTETSAMHPCTYEGCNKSFARPVLLSFHMKRVHKVDTPQRDFPCTECEKVFRCPTALKKHM 366

  Fly   299 RKHTGER-PFACKYCGR-------------------------CFTDYTTRV---KHERTHTNERP 334
            .|||||. ||||:.||:                         |....|||.   ||..|||.|:.
  Fly   367 YKHTGEELPFACEICGKRFPINSVLRDHLLRHAGIKNHVCPYCGVGKTTRQEWNKHILTHTKEKK 431

  Fly   335 Y-----------------------------VCGTCGKAFTTGYILKNHMLIHSGERAYRCELCDK 370
            |                             .|..|||.|...:..|.|...|:||:...|::|.|
  Fly   432 YECRQCDHASHNKQALANHVKVVHEKRKDFACQYCGKTFGKSHACKIHERSHTGEKCCECKICGK 496

  Fly   371 SFM----LPTHLSTHFRSGVHKRHLEKAE 395
            .|:    |..||.||     .||.|.|.:
  Fly   497 VFLFEKGLTKHLKTH-----EKRDLPKTQ 520

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
M1BPNP_649825.1 zf-AD 13..84 CDD:214871 13/70 (19%)
C2H2 Zn finger 253..273 CDD:275368 5/22 (23%)
COG5048 276..>331 CDD:227381 28/86 (33%)
C2H2 Zn finger 281..301 CDD:275368 7/19 (37%)
zf-H2C2_2 293..317 CDD:290200 16/49 (33%)
C2H2 Zn finger 309..329 CDD:275368 9/47 (19%)
zf-H2C2_2 324..346 CDD:290200 12/50 (24%)
C2H2 Zn finger 337..357 CDD:275368 7/19 (37%)
zf-H2C2_2 350..372 CDD:290200 8/21 (38%)
C2H2 Zn finger 365..383 CDD:275368 9/21 (43%)
D19BNP_477297.1 zf-AD 12..83 CDD:214871 13/78 (17%)
C2H2 Zn finger 255..275 CDD:275368 0/19 (0%)
C2H2 Zn finger 283..335 CDD:275368 8/60 (13%)
C2H2 Zn finger 318..338 CDD:275368 4/19 (21%)
COG5048 <347..512 CDD:227381 49/169 (29%)
C2H2 Zn finger 349..369 CDD:275368 7/19 (37%)
C2H2 Zn finger 378..398 CDD:275368 3/19 (16%)
C2H2 Zn finger 406..426 CDD:275368 6/19 (32%)
C2H2 Zn finger 434..455 CDD:275368 0/20 (0%)
C2H2 Zn finger 463..483 CDD:275368 7/19 (37%)
C2H2 Zn finger 491..511 CDD:275368 7/19 (37%)
C2H2 Zn finger 586..607 CDD:275368
C2H2 Zn finger 615..635 CDD:275368
zf-H2C2_2 627..652 CDD:290200
C2H2 Zn finger 643..663 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24388
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

Return to query results.
Submit another query.