DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment M1BP and Zfp945

DIOPT Version :9

Sequence 1:	NP_649825.1	Gene:	M1BP / 41042	FlyBaseID:	FBgn0037621	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001103724.1	Gene:	Zfp945 / 240041	MGIID:	2445132	Length:	794	Species:	Mus musculus

Alignment Length:	169	Identity:	61/169 - (36%)
Similarity:	91/169 - (53%)	Gaps:	9/169 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   220 EHENIVVKKCSLPPKPKVRSDDARRRGTGGVYICEQCGNHIKGRMAFELHCRRHRGDKQFGCELC 284
            |.||..::..||....::.|   |::    :|.|.:|...........:|.|.|.|:|.:.|..|
Mouse   627 EFENSFIQTGSLRIHQRLHS---RKK----LYKCRECDKSFTSSSYVRIHQRIHSGEKPYKCSEC 684

  Fly   285 QSRFCTTSELKRHMRKHTGERPFACKYCGRCFTDYTTRVKHERTHTNERPYVCGTCGKAFTTGYI 349
            ...|.:.|.|:.|.|.|||::|:.|..|.:|||...:...|:|:||.|:||.||.|.::||:|..
Mouse   685 GKCFTSGSYLRMHQRIHTGDKPYKCSDCDKCFTQKCSLRIHQRSHTGEKPYKCGNCDRSFTSGSY 749

  Fly   350 LKNHMLIHSGERAYRCELCDKSFMLPTHLSTHFRSGVHK 388
            |:.|..||.||:.::|..|||||....:|..|.|  :||
Mouse   750 LRIHQRIHRGEKPHKCSECDKSFTQKGYLRIHQR--IHK 786

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
M1BP	NP_649825.1	zf-AD	13..84	CDD:214871
		C2H2 Zn finger	253..273	CDD:275368	4/19 (21%)
		COG5048	276..>331	CDD:227381	20/54 (37%)
		C2H2 Zn finger	281..301	CDD:275368	7/19 (37%)
		zf-H2C2_2	293..317	CDD:290200	10/23 (43%)
		C2H2 Zn finger	309..329	CDD:275368	7/19 (37%)
		zf-H2C2_2	324..346	CDD:290200	11/21 (52%)
		C2H2 Zn finger	337..357	CDD:275368	8/19 (42%)
		zf-H2C2_2	350..372	CDD:290200	10/21 (48%)
		C2H2 Zn finger	365..383	CDD:275368	8/17 (47%)
Zfp945	NP_001103724.1	KRAB	34..92	CDD:214630
		KRAB	34..73	CDD:279668
		C2H2 Zn finger	205..225	CDD:275368
		C2H2 Zn finger	233..253	CDD:275368
		C2H2 Zn finger	261..281	CDD:275368
		C2H2 Zn finger	289..309	CDD:275368
		COG5048	340..754	CDD:227381	45/133 (34%)
		C2H2 Zn finger	345..365	CDD:275368
		zf-H2C2_2	358..382	CDD:290200
		C2H2 Zn finger	373..393	CDD:275368
		C2H2 Zn finger	401..421	CDD:275368
		zf-H2C2_2	414..437	CDD:290200
		C2H2 Zn finger	429..449	CDD:275368
		C2H2 Zn finger	457..477	CDD:275368
		zf-H2C2_2	469..494	CDD:290200
		C2H2 Zn finger	485..505	CDD:275368
		zf-H2C2_2	497..521	CDD:290200
		C2H2 Zn finger	513..533	CDD:275368
		C2H2 Zn finger	541..561	CDD:275368
		C2H2 Zn finger	569..589	CDD:275368
		C2H2 Zn finger	597..617	CDD:275368
		C2H2 Zn finger	625..645	CDD:275368	5/17 (29%)
		C2H2 Zn finger	653..673	CDD:275368	4/19 (21%)
		C2H2 Zn finger	681..701	CDD:275368	7/19 (37%)
		zf-H2C2_2	693..718	CDD:290200	11/24 (46%)
		C2H2 Zn finger	709..729	CDD:275368	7/19 (37%)
		zf-H2C2_2	721..746	CDD:290200	11/24 (46%)
		C2H2 Zn finger	737..757	CDD:275368	8/19 (42%)
		zf-H2C2_2	749..774	CDD:290200	12/24 (50%)
		C2H2 Zn finger	765..785	CDD:275368	9/21 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000