DRSC/TRiP Functional Genomics Resources

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Protein Alignment M1BP and ZNF595

DIOPT Version :9

Sequence 1:NP_649825.1 Gene:M1BP / 41042 FlyBaseID:FBgn0037621 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_872330.1 Gene:ZNF595 / 152687 HGNCID:27196 Length:648 Species:Homo sapiens


Alignment Length:183 Identity:64/183 - (34%)
Similarity:92/183 - (50%) Gaps:24/183 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   220 EHENI-------VVKKC--------SLPPKPKVRSDDARRRGTGGVYICEQCGNHIKGRMAFELH 269
            ||:||       ..:||        ||.....:.|:..       :|.||:||.......:...|
Human   329 EHKNIHTGEKPYTCEKCGKAFNQSSSLIIHRSIHSEQK-------LYKCEECGKAFTWSSSLNKH 386

  Fly   270 CRRHRGDKQFGCELCQSRFCTTSELKRHMRKHTGERPFACKYCGRCFTDYTTRVKHERTHTNERP 334
            .|.|.|:|.:.||.|...|..:|.|.:|.|.||||:|:.|:.||:.|...:|.:.|:|.|:.::|
Human   387 KRIHTGEKPYTCEECGKAFYRSSHLAKHKRIHTGEKPYTCEECGKAFNQSSTLILHKRIHSGQKP 451

  Fly   335 YVCGTCGKAFTTGYILKNHMLIHSGERAYRCELCDKSFMLPTHLSTHFRSGVH 387
            |.|..||||||....|..|..||:||:.|:||.|.|:|:....|:.|  ..:|
Human   452 YKCEECGKAFTRSTTLNEHKKIHTGEKPYKCEECGKAFIWSASLNEH--KNIH 502

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
M1BPNP_649825.1 zf-AD 13..84 CDD:214871
C2H2 Zn finger 253..273 CDD:275368 6/19 (32%)
COG5048 276..>331 CDD:227381 22/54 (41%)
C2H2 Zn finger 281..301 CDD:275368 8/19 (42%)
zf-H2C2_2 293..317 CDD:290200 11/23 (48%)
C2H2 Zn finger 309..329 CDD:275368 7/19 (37%)
zf-H2C2_2 324..346 CDD:290200 11/21 (52%)
C2H2 Zn finger 337..357 CDD:275368 9/19 (47%)
zf-H2C2_2 350..372 CDD:290200 11/21 (52%)
C2H2 Zn finger 365..383 CDD:275368 7/17 (41%)
ZNF595NP_872330.1 KRAB 4..64 CDD:214630
C2H2 Zn finger 147..167 CDD:275368
C2H2 Zn finger 175..194 CDD:275368
COG5048 198..599 CDD:227381 64/183 (35%)
C2H2 Zn finger 202..222 CDD:275368
C2H2 Zn finger 230..250 CDD:275368
C2H2 Zn finger 258..278 CDD:275368
C2H2 Zn finger 286..306 CDD:275368
C2H2 Zn finger 314..334 CDD:275368 3/4 (75%)
C2H2 Zn finger 342..362 CDD:275368 4/19 (21%)
C2H2 Zn finger 370..390 CDD:275368 6/19 (32%)
C2H2 Zn finger 398..418 CDD:275368 8/19 (42%)
C2H2 Zn finger 426..446 CDD:275368 7/19 (37%)
C2H2 Zn finger 454..474 CDD:275368 9/19 (47%)
C2H2 Zn finger 482..502 CDD:275368 7/21 (33%)
C2H2 Zn finger 510..530 CDD:275368
C2H2 Zn finger 538..558 CDD:275368
C2H2 Zn finger 566..586 CDD:275368
C2H2 Zn finger 594..614 CDD:275368
C2H2 Zn finger 622..642 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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