DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and CRZ1

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_014371.1	Gene:	CRZ1 / 855704	SGDID:	S000004972	Length:	678	Species:	Saccharomyces cerevisiae

Alignment Length:	273	Identity:	66/273 - (24%)
Similarity:	106/273 - (38%)	Gaps:	73/273 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 ESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQSSGFKVEDILNESKINEDEPNN-------- 147
            |..||:....|..|::|::....|  :|.|.....:......:.:|.|..|||..||
Yeast   432 EKAKSISANREKLLEMADLLPSSE--NDNNRERYDNDSKTSYNTINSSNFNEDNNNNNLLTSKPK 494

  Fly   148 --------EDDIDYSEMDY-LIYESDT--EVDAKQELKSDSENPKKRRNRRNPRDSNRTFFCEEC 201
                    ::::|.:..|. ::.:.|:  :.:.|...|:|.       |..|  :.|.||..::.
Yeast   495 IESGIVNIKNELDDTSKDLGILLDIDSLGQFEQKVGFKNDD-------NHEN--NDNGTFSVKKN 550

  Fly   202 GNHIK-DRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYS 265
            .|..| |.::     ...:....|.|:.|..:|..|..||.|:
Yeast   551 DNLEKLDSVT-----NNRKNPANFACDVCGKKFTRPYNLKSHL---------------------- 588

  Fly   266 TRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCD---------LCDKLFSRYT 321
                  |||||||||:|..|..||...:..|.|..:|||:|.:.|.         .|.|.|:|..
Yeast   589 ------RTHTNERPFICSICGKAFARQHDRKRHEDLHTGKKRYVCGGKLKDGKPWGCGKKFARSD 647

  Fly   322 HLTTHYRSNAHRR 334
            .|..|:::.:.||
Yeast   648 ALGRHFKTESGRR 660

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	3/20 (15%)
		COG5048	222..>276	CDD:227381	11/53 (21%)
		C2H2 Zn finger	226..246	CDD:275368	7/19 (37%)
		zf-H2C2_2	238..262	CDD:290200	3/23 (13%)
		C2H2 Zn finger	254..274	CDD:275368	1/19 (5%)
		zf-H2C2_2	269..291	CDD:290200	13/21 (62%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	10/32 (31%)
		C2H2 Zn finger	310..328	CDD:275368	7/26 (27%)
CRZ1	NP_014371.1	COG5048	139..617	CDD:227381	53/228 (23%)
		C2H2 Zn finger	571..591	CDD:275368	8/47 (17%)
		C2H2 Zn finger	599..619	CDD:275368	6/19 (32%)
		C2H2 Zn finger	627..655	CDD:275368	7/27 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100