DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and ZAP1

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_012479.1	Gene:	ZAP1 / 853390	SGDID:	S000003592	Length:	880	Species:	Saccharomyces cerevisiae

Alignment Length:	155	Identity:	51/155 - (32%)
Similarity:	82/155 - (52%)	Gaps:	10/155 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   193 NRTF-FCEECGNHIKDRISFILHCKRHRGVKEFGCEF--CEDRFCTPAELKRHIRKHTGEKPFKC 254
            |::| ..:|..:|::     .:|..  ||..|:.|.:  |...|....:|.||::.|:..||:||
Yeast   713 NKSFSSAQELNDHLE-----AVHLT--RGKSEYQCLWHDCHRTFPQRQKLIRHLKVHSKYKPYKC 770

  Fly   255 RHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSR 319
            :.|.|.||...|.::|.|||:.|:|:.|..||..|..|..||.|:..|||||..:|.:|.|.|:.
Yeast   771 KTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTHTGEKPLQCKICGKRFNE 835

  Fly   320 YTHLTTHYRSNAHRRNMQKADTIFD 344
            .::|:.|.:::..:.........||
Yeast   836 SSNLSKHIKTHQKKYKCSDCSKSFD 860

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	3/19 (16%)
		COG5048	222..>276	CDD:227381	21/55 (38%)
		C2H2 Zn finger	226..246	CDD:275368	6/21 (29%)
		zf-H2C2_2	238..262	CDD:290200	10/23 (43%)
		C2H2 Zn finger	254..274	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..291	CDD:290200	10/21 (48%)
		C2H2 Zn finger	282..302	CDD:275368	8/19 (42%)
		zf-H2C2_2	295..319	CDD:290200	12/23 (52%)
		C2H2 Zn finger	310..328	CDD:275368	6/17 (35%)
ZAP1	NP_012479.1	COG5048	292..761	CDD:227381	14/54 (26%)
		C2H2 Zn finger	743..762	CDD:275368	5/18 (28%)
		SUF4-like	766..>814	CDD:411020	22/47 (47%)
		C2H2 Zn finger	770..795	CDD:411020	11/24 (46%)
		C2H2 Zn finger	770..790	CDD:275368	8/19 (42%)
		C2H2 Zn finger	798..818	CDD:275368	8/19 (42%)
		zf-H2C2_2	810..834	CDD:404364	11/23 (48%)
		C2H2 Zn finger	826..846	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000