Protein Alignment ranshi and ZNF528

DIOPT Version :9

• Sequence 1: NP_649824.1
• Gene: ranshi / 41041
• FlyBaseID: FBgn0037620
• Length: 346
• Species: Drosophila melanogaster
• Sequence 2: XP_006723481.1
• Gene: ZNF528 / 84436
• HGNCID: 29384
• Length: 712
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 73/244 - (29%)
• Similarity: 108/244 - (44%)
• Gaps: 29/244 - (11%)

  Fly    97 LEQEELELDLAEISI------EVERLDDLNEGPIQSSGFKVED-ILNESKINEDEP---NNEDDI 151
            |...:|:|..||..|      |....|:.:..|::.....|:. :||:.:.|.|..   ..|...
Human   199 LHLSDLQLFQAERKISGCKHFEKPVSDNSSVSPLEKISSSVKSHLLNKYRNNFDHAPLLPQEQKA 263

  Fly   152 DYSEMDYLIYESDTEVDAKQELKS----DSENPKKRRNRRNPRDSNRTFFCEECGNHIKDRISFI 212
            ...|..|...|......|...|.:    :::||.|               |.|||.........:
Human   264 HIREKAYKCNEHGQVFRASASLTNQVIHNADNPYK---------------CSECGKVFSCSSKLV 313

  Fly   213 LHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNE 277
            :|.:.|.|.|.:.|..|...|.:.:.|.:|.|.||||||:||..|.:.|...|...:|:|.||.|
Human   314 IHRRMHTGEKPYKCHECGKLFSSNSNLSQHQRIHTGEKPYKCHECDKVFRSSSKLAQHQRIHTGE 378

  Fly   278 RPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTH 326
            :|:.|.||:..|.....|..|..:|||||.:.|:.|.|:|||:::|..|
Human   379 KPYKCHECDKVFNQIAHLVRHQKIHTGEKPYSCNKCGKVFSRHSYLAEH 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	5/19 (26%)
		COG5048	222..>276	CDD:227381	21/53 (40%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	12/23 (52%)
		C2H2 Zn finger	254..274	CDD:275368	6/19 (32%)
		zf-H2C2_2	269..291	CDD:290200	10/21 (48%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	11/23 (48%)
		C2H2 Zn finger	310..328	CDD:275368	8/17 (47%)
ZNF528	XP_006723481.1	KRAB	8..68	CDD:214630
		KRAB	8..47	CDD:279668
		C2H2 Zn finger	272..291	CDD:275368	3/18 (17%)
		COG5048	277..712	CDD:227381	55/166 (33%)
		C2H2 Zn finger	299..319	CDD:275368	5/19 (26%)
		zf-H2C2_2	312..336	CDD:290200	7/23 (30%)
		C2H2 Zn finger	327..347	CDD:275368	6/19 (32%)
		zf-H2C2_2	339..364	CDD:290200	13/24 (54%)
		C2H2 Zn finger	355..375	CDD:275368	6/19 (32%)
		zf-H2C2_2	368..392	CDD:290200	10/23 (43%)
		C2H2 Zn finger	383..403	CDD:275368	6/19 (32%)
		zf-H2C2_2	395..420	CDD:290200	11/24 (46%)
		C2H2 Zn finger	411..431	CDD:275368	8/17 (47%)
		zf-H2C2_2	423..447	CDD:290200	2/5 (40%)
		C2H2 Zn finger	439..459	CDD:275368
		C2H2 Zn finger	467..487	CDD:275368
		C2H2 Zn finger	495..515	CDD:275368
		C2H2 Zn finger	523..543	CDD:275368
		zf-H2C2_2	535..560	CDD:290200
		C2H2 Zn finger	551..571	CDD:275368
		zf-H2C2_2	563..588	CDD:290200
		C2H2 Zn finger	579..599	CDD:275368
		zf-H2C2_2	591..616	CDD:290200
		C2H2 Zn finger	607..627	CDD:275368
		zf-H2C2_2	619..642	CDD:290200
		C2H2 Zn finger	635..655	CDD:275368
		C2H2 Zn finger	663..683	CDD:275368
		zf-H2C2_2	675..700	CDD:290200
		C2H2 Zn finger	691..711	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000