DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and si:dkey-262g12.12

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_017211312.1	Gene:	si:dkey-262g12.12 / 798048	ZFINID:	ZDB-GENE-161017-24	Length:	355	Species:	Danio rerio

Alignment Length:	241	Identity:	71/241 - (29%)
Similarity:	108/241 - (44%)	Gaps:	44/241 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 QSSGFKVEDILNESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSD-------SENPKK 182
            :|...|:||..        ...:||..:.:|:..:..|:....:.:|:.:.|       .|...|
Zfish     7 ESEDLKIEDTF--------VVKHEDPQEQTELMVMKEETQDRNETQQKCQYDKHQDSTLDEKSLK 63

  Fly   183 RRNRRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHI---- 243
            ::..|.| ...|.:.|.:|....::|.:..:|.:.|.|.|.|.|:.|..||.....||.|:
Zfish    64 KKCERIP-TGERMYTCPQCEKSFRERQALEIHIRIHTGEKPFSCDHCGRRFSQKPNLKAHMSIHT 127

  Fly   244 ------------------------RKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKE 284
                                    |.|||||||.|:.|.:.|:..:....|.||||.|:||.|::
Zfish   128 AEKPYSCSECGKSFRAKKQLEGHTRVHTGEKPFACQQCGKRFAYQAAFRTHTRTHTGEKPFTCEQ 192

  Fly   285 CNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYRSN 330
            |..:||.|..:|.||.||||||.:.|..|.|.|:..|:|..|.|::
Zfish   193 CGKSFTHSEYMKAHMRVHTGEKPYTCSQCGKTFAHRTNLYVHRRTH 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	4/19 (21%)
		COG5048	222..>276	CDD:227381	24/81 (30%)
		C2H2 Zn finger	226..246	CDD:275368	8/47 (17%)
		zf-H2C2_2	238..262	CDD:290200	13/51 (25%)
		C2H2 Zn finger	254..274	CDD:275368	5/19 (26%)
		zf-H2C2_2	269..291	CDD:290200	11/21 (52%)
		C2H2 Zn finger	282..302	CDD:275368	8/19 (42%)
		zf-H2C2_2	295..319	CDD:290200	13/23 (57%)
		C2H2 Zn finger	310..328	CDD:275368	7/17 (41%)
si:dkey-262g12.12	XP_017211312.1	C2H2 Zn finger	78..98	CDD:275368	4/19 (21%)
		COG5048	<90..346	CDD:227381	53/149 (36%)
		C2H2 Zn finger	106..126	CDD:275368	7/19 (37%)
		C2H2 Zn finger	134..154	CDD:275368	1/19 (5%)
		C2H2 Zn finger	162..182	CDD:275368	5/19 (26%)
		C2H2 Zn finger	190..210	CDD:275368	8/19 (42%)
		C2H2 Zn finger	218..238	CDD:275368	8/19 (42%)
		C2H2 Zn finger	246..266	CDD:275368
		C2H2 Zn finger	274..294	CDD:275368
		C2H2 Zn finger	302..322	CDD:275368
		C2H2 Zn finger	330..350	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910