DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and zgc:175107

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001107104.1	Gene:	zgc:175107 / 794317	ZFINID:	ZDB-GENE-080220-38	Length:	333	Species:	Danio rerio

Alignment Length:	331	Identity:	85/331 - (25%)
Similarity:	143/331 - (43%)	Gaps:	42/331 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KRTNAERSLNIFEKRNQTTLE---HIKLLTGAVLKNCSTLPNR---LCASCQTCLQQAISFRERC 69
            :.||.....|.::||:....|   |.:  ..::||...:..:.   :|..|    .::...::.
Zfish    38 QETNELEERNQYDKRDSAIGEKSTHTQ--DASLLKRPQSAESSGYYICGEC----NKSFGLKQN- 95

  Fly    70 LEVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQSSGFKVEDI 134
            |||.:. .|: .::.|  .||:..||..:::.|::.:..         ...|.|. |..|..::.
Zfish    96 LEVHKR-THT-GEKPF--SCQQCGKSFSQKQNLKVHMRV---------HTGEKPF-SCPFCGQNF 146

  Fly   135 LNESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDSENPKKRRNRRNPRDSNRTFFCE 199
            .::..:.....|:..:..:.          ..:..|...:.:|.|...|.:     ...:.|.|.
Zfish   147 THKGNLKTHVRNHTGESAFI----------CNLCGKSFSRKESLNTHMRIH-----SGEKPFGCA 196

  Fly   200 ECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDY 264
            :||...:.:::...|.:.|.....|.|..||..|....||:.|:..|.|||||.|.||.:|.|:.
Zfish   197 QCGKTFRCKVNLNCHMRIHSRESSFICHHCEQSFGDSDELRSHVNTHVGEKPFMCLHCGKSCSNK 261

  Fly   265 STRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYRS 329
            :....|.|.||.||||||.:|..:||....|..|:.||||||.|.|..|:|.|:.:|.|..|.:|
Zfish   262 AVLEVHSRIHTGERPFVCPQCGKSFTLRGNLNIHIRVHTGEKPFNCVHCEKSFTYHTDLKRHLQS 326

  Fly   330 NAHRRN 335
            ...:.:
Zfish   327 PCEKNS 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	14/71 (20%)
		C2H2 Zn finger	198..218	CDD:275368	4/19 (21%)
		COG5048	222..>276	CDD:227381	22/53 (42%)
		C2H2 Zn finger	226..246	CDD:275368	7/19 (37%)
		zf-H2C2_2	238..262	CDD:290200	13/23 (57%)
		C2H2 Zn finger	254..274	CDD:275368	7/19 (37%)
		zf-H2C2_2	269..291	CDD:290200	12/21 (57%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	13/23 (57%)
		C2H2 Zn finger	310..328	CDD:275368	7/17 (41%)
zgc:175107	NP_001107104.1	C2H2 Zn finger	83..103	CDD:275368	5/25 (20%)
		zf-H2C2_2	95..120	CDD:290200	9/29 (31%)
		COG5048	<107..286	CDD:227381	51/205 (25%)
		C2H2 Zn finger	111..131	CDD:275368	5/28 (18%)
		zf-H2C2_2	123..148	CDD:290200	5/34 (15%)
		C2H2 Zn finger	139..159	CDD:275368	1/19 (5%)
		zf-C2H2	165..187	CDD:278523	4/31 (13%)
		C2H2 Zn finger	167..187	CDD:275368	4/19 (21%)
		C2H2 Zn finger	195..215	CDD:275368	4/19 (21%)
		C2H2 Zn finger	223..243	CDD:275368	7/19 (37%)
		C2H2 Zn finger	251..271	CDD:275368	7/19 (37%)
		zf-H2C2_2	264..287	CDD:290200	11/22 (50%)
		C2H2 Zn finger	279..299	CDD:275368	6/19 (32%)
		zf-H2C2_2	291..316	CDD:290200	13/24 (54%)
		C2H2 Zn finger	307..324	CDD:275368	6/16 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910