DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ranshi and Zkscan1

DIOPT Version :9

Sequence 1:NP_649824.1 Gene:ranshi / 41041 FlyBaseID:FBgn0037620 Length:346 Species:Drosophila melanogaster
Sequence 2:NP_598667.2 Gene:Zkscan1 / 74570 MGIID:1921820 Length:561 Species:Mus musculus


Alignment Length:449 Identity:103/449 - (22%)
Similarity:154/449 - (34%) Gaps:173/449 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly    49 NRLCASCQTCLQQAISFRERCLEVQRELLHSQDDEDFLRICQESPKSVLEQ-------------E 100
            |||...|...|:..::.:|:.||:.  :|     |.||.|..:..:..|::             |
Mouse    75 NRLKELCHQWLRPEVNSKEQILELL--VL-----EQFLSILPKELQVWLQEYRPDSGEEAVTLLE 132

  Fly   101 ELELDLA--EISIEVERLDDLNEG-----PIQ-SSGF---------------------------- 129
            :|||||:  ::..:|...:.|..|     |:| ||.|                            
Mouse   133 DLELDLSGQQVPGQVHGPEMLARGVVPLDPVQESSSFDHHETAQSHFKHSSRKPRLLSRALPATH 197

  Fly   130 ----------------------------KVED-----ILNE--------SKINED---------- 143
                                        |:||     ||.|        ..:|.|          
Mouse   198 VPAPHHEGNPRDQAMASALLTADSQAMVKIEDMAVSLILEEWGCQNLARRNLNRDSRQMNLGNVF 262

  Fly   144 ----EPNN-----------EDDIDYSEMDYLIYESDTEVDAKQE-----LKSDSENPKKRRNR-- 186
                |..|           ||...:.|   :......|...|:|     ::...:||:::..:  
Mouse   263 SQGSENRNGNESTSKAEVKEDSTSHGE---IAGRFQKEFGEKREQQGRVVERQQKNPEEKTGKEK 324

  Fly   187 -----------------RNPRDSN------------------------RTFFCEECGNHIKDRIS 210
                             |.||:..                        :|..|:|||.......|
Mouse   325 KEPGPPTAKEKKPSTGERGPREKGKGLGRSFSLSANFNNTPEEAPSGAKTHRCDECGKCFTRSSS 389

  Fly   211 FILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHT 275
            .|.|...|.|.|.:.|..|...|...:.|..|.|.||||||.:|..|.::||..|..:.|:|.|:
Mouse   390 LIRHKIIHTGEKPYECNECGKAFSLNSNLVLHQRIHTGEKPHECNECGKAFSHSSNLILHQRIHS 454

  Fly   276 NERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYRSNAHRR 334
            .|:|:.|.||..||:.|..|..|..:|||||.:.|..|.|.|:|.::|..|.|.:...:
Mouse   455 GEKPYECNECGKAFSQSSDLTKHQRIHTGEKPYECSECGKAFNRNSYLILHRRIHTREK 513

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ranshiNP_649824.1 zf-AD 5..77 CDD:214871 8/27 (30%)
C2H2 Zn finger 198..218 CDD:275368 7/19 (37%)
COG5048 222..>276 CDD:227381 21/53 (40%)
C2H2 Zn finger 226..246 CDD:275368 6/19 (32%)
zf-H2C2_2 238..262 CDD:290200 11/23 (48%)
C2H2 Zn finger 254..274 CDD:275368 7/19 (37%)
zf-H2C2_2 269..291 CDD:290200 10/21 (48%)
C2H2 Zn finger 282..302 CDD:275368 8/19 (42%)
zf-H2C2_2 295..319 CDD:290200 11/23 (48%)
C2H2 Zn finger 310..328 CDD:275368 7/17 (41%)
Zkscan1NP_598667.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..51
SCAN 52..162 CDD:128708 23/93 (25%)
SCAN 52..129 CDD:280241 14/60 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 163..187 4/23 (17%)
KRAB 225..263 CDD:279668 8/37 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 260..372 13/114 (11%)
COG5048 <354..535 CDD:227381 54/160 (34%)
zf-C2H2 375..397 CDD:278523 7/21 (33%)
C2H2 Zn finger 377..397 CDD:275368 7/19 (37%)
zf-H2C2_2 389..413 CDD:290200 8/23 (35%)
C2H2 Zn finger 405..425 CDD:275368 6/19 (32%)
zf-H2C2_2 417..442 CDD:290200 12/24 (50%)
C2H2 Zn finger 433..453 CDD:275368 7/19 (37%)
zf-H2C2_2 445..470 CDD:290200 10/24 (42%)
C2H2 Zn finger 461..481 CDD:275368 8/19 (42%)
zf-H2C2_2 473..498 CDD:290200 11/24 (46%)
C2H2 Zn finger 489..509 CDD:275368 8/19 (42%)
zf-H2C2_2 501..526 CDD:290200 3/13 (23%)
C2H2 Zn finger 517..537 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.