DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and znf281

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_002935748.1	Gene:	znf281 / 733827	XenbaseID:	XB-GENE-5933312	Length:	796	Species:	Xenopus tropicalis

Alignment Length:	256	Identity:	69/256 - (26%)
Similarity:	113/256 - (44%)	Gaps:	52/256 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 DFLR----ICQESPKSVLEQEEL------ELDLAEISIEVERLDDLNEGPIQSSGFKVEDILNES 138
            |||:    |.||   .:.|.|:.      :.::.|:::         .||    |...|..||..
Frog    58 DFLQGLAGIKQE---KIGEHEQYRFYGDRQAEIVEVTV---------GGP----GLIPELGLNRE 106

  Fly   139 KINEDEPNNEDDIDYSEMDYLIYESDTEVDAKQELKSDSENPKKRRNRRNPRDSNRTFFCEECGN 203
            .:...|.|..|              .||:.:.::.|..:...::.:::|...||:::...:
Frog   107 LLIRTEKNGFD--------------PTEIPSNKKTKRLNSEAQEAKSKRRRSDSSKSVGGD---- 153

  Fly   204 HIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTRL 268
              .:..|...:.|.|.      ||.|...|.:...|:||:..||||:||:|..|:.||.......
Frog   154 --GEAASLSPNQKPHI------CEHCSAAFRSSYHLRRHVLIHTGERPFQCSQCNMSFIQKYLLQ 210

  Fly   269 KHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYRS 329
            :||:.|:.|:||.|.:||..|...|.::.|...|:|||.::||.|.:.|||...|..|.|:
Frog   211 RHEKIHSGEKPFNCDQCNMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRLLKHKRT 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	2/19 (11%)
		COG5048	222..>276	CDD:227381	20/53 (38%)
		C2H2 Zn finger	226..246	CDD:275368	7/19 (37%)
		zf-H2C2_2	238..262	CDD:290200	12/23 (52%)
		C2H2 Zn finger	254..274	CDD:275368	6/19 (32%)
		zf-H2C2_2	269..291	CDD:290200	10/21 (48%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	9/23 (39%)
		C2H2 Zn finger	310..328	CDD:275368	8/17 (47%)
znf281	XP_002935748.1	PS_II_S4	<53..>134	CDD:132113	21/105 (20%)
		zf-C2H2	166..188	CDD:333835	8/27 (30%)
		C2H2 Zn finger	168..188	CDD:275368	7/19 (37%)
		zf-H2C2_2	180..205	CDD:372612	13/24 (54%)
		C2H2 Zn finger	196..216	CDD:275368	6/19 (32%)
		zf-H2C2_2	209..233	CDD:372612	10/23 (43%)
		C2H2 Zn finger	224..244	CDD:275368	6/19 (32%)
		zf-H2C2_2	236..261	CDD:372612	9/24 (38%)
		C2H2 Zn finger	252..271	CDD:275368	8/18 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910