DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and Zfp661

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_011238089.1	Gene:	Zfp661 / 72180	MGIID:	1919430	Length:	454	Species:	Mus musculus

Alignment Length:	241	Identity:	67/241 - (27%)
Similarity:	100/241 - (41%)	Gaps:	56/241 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 IYESDTEVDAKQELKS-------DSENPKKRRNRRNPRDSNRTFF-----------------CEE 200
            |:...:.:..|:|:::       :.|:||.|..:: |...::...                 |.|
Mouse   137 IHRKQSSLCPKREIQTLTGGPEPEKESPKARTCKK-PLSLDKGLHQMSAPSKKALTKHQDQECSE 200

  Fly   201 CGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHI---------------------- 243
            ||....|..|.|.|.:.|.|.|.:.|..|...|...:.|.||:
Mouse   201 CGKTFFDHSSLIRHQRTHTGEKPYDCPECGKAFSHRSSLSRHLMFHTGESPYECDACGKAFFDRS 265

  Fly   244 ------RKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVH 302
                  |.|||||||||..|.::|.|.|:..:|:|.||.|.|:.|::|..||:...||..|:|.|
Mouse   266 SLTVHQRIHTGEKPFKCNDCGKAFFDRSSLTRHQRIHTGESPYECQQCGKAFSQKSILTRHLLTH 330

  Fly   303 TGEKAFRCDLCDKLFSRYTHLTTHYRSNAHRRNMQKAD---TIFDK 345
            ||.|.:.|..|.|.|...|.|..|.:.:......|.::   ..||:
Mouse   331 TGRKPYECRDCGKAFYGVTSLNRHQKVHTEEPRYQCSECGKAFFDR 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	8/19 (42%)
		COG5048	222..>276	CDD:227381	24/81 (30%)
		C2H2 Zn finger	226..246	CDD:275368	7/47 (15%)
		zf-H2C2_2	238..262	CDD:290200	14/51 (27%)
		C2H2 Zn finger	254..274	CDD:275368	7/19 (37%)
		zf-H2C2_2	269..291	CDD:290200	10/21 (48%)
		C2H2 Zn finger	282..302	CDD:275368	8/19 (42%)
		zf-H2C2_2	295..319	CDD:290200	11/23 (48%)
		C2H2 Zn finger	310..328	CDD:275368	7/17 (41%)
Zfp661	XP_011238089.1	KRAB	51..101	CDD:214630
		COG5048	180..>444	CDD:227381	59/197 (30%)
		C2H2 Zn finger	198..218	CDD:275368	8/19 (42%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		C2H2 Zn finger	254..274	CDD:275368	1/19 (5%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..330	CDD:275368	8/19 (42%)
		C2H2 Zn finger	338..358	CDD:275368	7/19 (37%)
		C2H2 Zn finger	366..386	CDD:275368	2/11 (18%)
		C2H2 Zn finger	394..414	CDD:275368
		C2H2 Zn finger	422..440	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910