DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and CG18764

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_652712.2	Gene:	CG18764 / 59239	FlyBaseID:	FBgn0042205	Length:	409	Species:	Drosophila melanogaster

Alignment Length:	404	Identity:	136/404 - (33%)
Similarity:	191/404 - (47%)	Gaps:	73/404 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRERCL 70
            |||||.....:...|:|...|:..|:.|.|:||..|.|...||:.:||.|...|.|||.|||||:
  Fly     5 CRTCGSIIYNKMPKNLFHIENEKMLQDINLVTGTTLHNDPELPSSICACCTLDLNQAILFRERCI 69

  Fly    71 EVQRELLH----------SQDDEDFL--------------RICQESPKSVLEQE-----ELELDL 106
            ..|::|:|          ::|.|:..              ....|||:.||:.:     :|:.|.
  Fly    70 LTQKQLVHRRRSPEAKEPAEDVEEMASPPDCLNDPFGEVDEYIVESPEEVLDHDSDAHHDLDEDN 134

  Fly   107 AEISIE-VERLDDLNEGPIQSSGFKVEDILN------ESKINEDEPNNEDDIDYSEMDYLIYESD 164
            ...|:| |:.|.|:.|...:.|. .||.:::      ||..|:|  :|.|:.||.|.....|.::
  Fly   135 YIDSVEDVDALQDMAEVAEEDSQ-DVESLISSVQKELESICNDD--SNSDNNDYMEPQNGSYFNE 196

  Fly   165 T----EVD-------------AKQELKSDSENPKKRRN-------------RRNPRDSNRTFFCE 199
            |    ||.             |.:..|..:..||:::.             .|......|...||
  Fly   197 TINEYEVSSNPNTPLPESKSAAGRSTKPATTKPKRKKQYVTWKNMTEEQIIERKRLQRKRECVCE 261

  Fly   200 ECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIR-KHTGEKPFKCRHCSRSFSD 263
            :||....|:.:|.||..||.|.|.|.|:.|..||.|...:..|.| .|.||||:.||.|::||.:
  Fly   262 QCGRQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMTLHQRIIHQGEKPYDCRFCTKSFHN 326

  Fly   264 YSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYR 328
            .:|||.|||||||.:|:.|..|:..|.::...|.|.|:|||.:||.|.:|.:.|.|.|||..|.|
  Fly   327 SNTRLIHERTHTNAKPYSCHHCDKCFKSASGRKRHELIHTGVRAFACTICKQSFQRNTHLKAHLR 391

  Fly   329 SNAHRRNMQKADTI 342
            |..|   ..||.||
  Fly   392 SKFH---TAKAKTI 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	30/70 (43%)
		C2H2 Zn finger	198..218	CDD:275368	8/19 (42%)
		COG5048	222..>276	CDD:227381	27/54 (50%)
		C2H2 Zn finger	226..246	CDD:275368	7/20 (35%)
		zf-H2C2_2	238..262	CDD:290200	11/24 (46%)
		C2H2 Zn finger	254..274	CDD:275368	11/19 (58%)
		zf-H2C2_2	269..291	CDD:290200	11/21 (52%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	11/23 (48%)
		C2H2 Zn finger	310..328	CDD:275368	8/17 (47%)
CG18764	NP_652712.2	zf-AD	4..75	CDD:214871	30/69 (43%)
		C2H2 Zn finger	260..280	CDD:275368	8/19 (42%)
		zf-H2C2_2	272..297	CDD:290200	12/24 (50%)
		C2H2 Zn finger	288..309	CDD:275368	7/20 (35%)
		C2H2 Zn finger	317..337	CDD:275368	11/19 (58%)
		C2H2 Zn finger	345..365	CDD:275368	6/19 (32%)
		C2H2 Zn finger	373..391	CDD:275368	8/17 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26093
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.870