DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and si:ch211-79k12.2

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001313520.1	Gene:	si:ch211-79k12.2 / 568844	ZFINID:	ZDB-GENE-131121-535	Length:	555	Species:	Danio rerio

Alignment Length:	177	Identity:	59/177 - (33%)
Similarity:	85/177 - (48%)	Gaps:	12/177 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 ESDTEVDAKQELK---SDSENPKKRRNRRNPRDSNRT----FFCEECGNHIKDRISFILHCKRHR 219
            :...:.|..|:|.   .::..|:..:..::.|..:.|    |.|.|||.......:..:|...|.
Zfish   268 QGHAQQDGLQQLSCMHCNASFPRPSQLLQHQRTQHATKAGGFLCAECGRAFNSHSNLRIHLNVHT 332

  Fly   220 GVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKE 284
            |.:.:.|..|...|.....||.|.|.||||:|:.|.:|.|.|...:....|:|.||.|:|::|.:
Zfish   333 GARPYICTNCGKSFSQSGALKIHRRIHTGERPYTCSYCGRGFPHLAGVRAHQRIHTGEKPYICGQ 397

  Fly   285 CNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFS-----RYTHLTTH 326
            |...||.|..||.|..:||||:.|.|.||.|.||     |:.|.|.|
Zfish   398 CGKCFTQSGALKIHTRIHTGERPFVCGLCGKSFSNRSGIRFHHRTVH 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	5/19 (26%)
		COG5048	222..>276	CDD:227381	19/53 (36%)
		C2H2 Zn finger	226..246	CDD:275368	7/19 (37%)
		zf-H2C2_2	238..262	CDD:290200	12/23 (52%)
		C2H2 Zn finger	254..274	CDD:275368	6/19 (32%)
		zf-H2C2_2	269..291	CDD:290200	9/21 (43%)
		C2H2 Zn finger	282..302	CDD:275368	8/19 (42%)
		zf-H2C2_2	295..319	CDD:290200	14/28 (50%)
		C2H2 Zn finger	310..328	CDD:275368	10/22 (45%)
si:ch211-79k12.2	NP_001313520.1	C2H2 Zn finger	281..302	CDD:275368	2/20 (10%)
		C2H2 Zn finger	311..331	CDD:275368	5/19 (26%)
		zf-H2C2_2	323..348	CDD:290200	6/24 (25%)
		C2H2 Zn finger	339..359	CDD:275368	7/19 (37%)
		zf-H2C2_2	351..374	CDD:290200	12/22 (55%)
		C2H2 Zn finger	367..387	CDD:275368	6/19 (32%)
		zf-H2C2_2	380..404	CDD:290200	9/23 (39%)
		C2H2 Zn finger	395..415	CDD:275368	8/19 (42%)
		zf-H2C2_2	407..432	CDD:290200	13/24 (54%)
		C2H2 Zn finger	423..442	CDD:275368	8/18 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910