DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and AgaP_AGAP007971

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_001689041.1	Gene:	AgaP_AGAP007971 / 5668194	VectorBaseID:	AGAP007971	Length:	387	Species:	Anopheles gambiae

Alignment Length:	370	Identity:	70/370 - (18%)
Similarity:	103/370 - (27%)	Gaps:	146/370 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 GKVCRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTL----------PN---RLCAS 54
            ||.|..||.........|..| ||.|..:...:..|....|..:|          ||   :...:
Mosquito   126 GKACAVCGVMFGRLNQCNAHE-RNHTARKVNCVACGKEFNNSKSLYRHEQIVHVDPNSRKKYICN 189

  Fly    55 CQTCLQQ-----AISFRERCLEVQRE---------------LLHSQDDEDFLRICQESPKSVLEQ 99
            |..|.|.     .:...:|.:.|.|.               ::|..:.||....|....|....:
Mosquito   190 CNICYQTFTTACGMRVHQRAMRVLRYQCAVCGKLFGNRAACIIHETNHEDHQLSCDLCAKKFTNR 254

  Fly   100 EELELDLAEISIEVERLDDLNEGPIQSSGFKVEDILNESKINEDEPNNEDDIDYSEMDYLIYESD 164
            :.|.:.
Mosquito   255 KYLNIH----------------------------------------------------------- 260

  Fly   165 TEVDAKQELKSDSENPKKRRNRRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFC 229
                 ||.:.:|.|..||             :.|..||..:                       |
Mosquito   261 -----KQNVHTDPETRKK-------------YVCNVCGTSL-----------------------C 284

  Fly   230 EDRFCTPAELKRHIRKHTGEKPFKCRHCSRSF-SDYSTRLKHERTHTNE---RPFVCKECNNAFT 290
                ||...|..|.|.|: |..:.|..|.:.| .:...|...|..|.::   :.:||..|.....
Mosquito   285 ----CTLKHLMHHERTHS-EPSYSCADCGKEFVHEMQLRNHREAKHLDKSARKKYVCDVCGKELL 344

  Fly   291 TSYILKNHMLV-HTGEKAFRCDLCDKLFSRYTHLTTHYRSNAHRR 334
            ....|:.|.|| |:||:.:.|:|||..|....:||:|  ...|.|
Mosquito   345 AKVSLRKHTLVMHSGERPYACNLCDARFQIKAYLTSH--MTVHNR 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	19/104 (18%)
		C2H2 Zn finger	198..218	CDD:275368	3/19 (16%)
		COG5048	222..>276	CDD:227381	14/54 (26%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	8/24 (33%)
		C2H2 Zn finger	254..274	CDD:275368	5/20 (25%)
		zf-H2C2_2	269..291	CDD:290200	5/24 (21%)
		C2H2 Zn finger	282..302	CDD:275368	6/20 (30%)
		zf-H2C2_2	295..319	CDD:290200	12/24 (50%)
		C2H2 Zn finger	310..328	CDD:275368	8/17 (47%)
AgaP_AGAP007971	XP_001689041.1	C2H2 Zn finger	33..53	CDD:275368
		C2H2 Zn finger	60..80	CDD:275368
		C2H2 Zn finger	87..108	CDD:275368
		C2H2 Zn finger	122..149	CDD:275368	8/23 (35%)
		C2H2 Zn finger	156..172	CDD:275368	3/15 (20%)
		C2H2 Zn finger	190..208	CDD:275368	3/17 (18%)
		C2H2 Zn finger	217..237	CDD:275368	1/19 (5%)
		C2H2 Zn finger	244..265	CDD:275368	5/84 (6%)
		C2H2 Zn finger	276..297	CDD:275368	9/47 (19%)
		C2H2 Zn finger	304..325	CDD:275368	5/20 (25%)
		C2H2 Zn finger	336..357	CDD:275368	6/20 (30%)
		C2H2 Zn finger	365..385	CDD:275368	8/21 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000