DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and AgaP_AGAP004541

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_001688465.2	Gene:	AgaP_AGAP004541 / 5667453	VectorBaseID:	AGAP004541	Length:	2515	Species:	Anopheles gambiae

Alignment Length:	371	Identity:	83/371 - (22%)
Similarity:	132/371 - (35%)	Gaps:	125/371 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTCGKRTNAERSL------------NIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRL-CASCQT 57
            ||.|....:..|.|            .|||   .||:| |.|.:.         |:.| |.||..
Mosquito    45 CRLCCNEDSHLRELFAGGYKEELLVRKIFE---CTTVE-ITLASD---------PDALICYSCVA 96

  Fly    58 CLQQAISFRERCLEVQRELLHSQDDEDF---LRICQESPKSVLE----QEELELDLAEIS----- 110
            .:::...:||:|.  ..::||.......   :.....|...:|.    ::|.:::..||:
Mosquito    97 KIEEFHHYREQCR--TNDVLHRNWKRRLGGQIATASSSSSMILPAKYIKKEKDVESFEINAGDFF 159

  Fly   111 -IEV-ERLDDL--NEGPIQS--SGFKVEDILNESKINEDEPNN-EDDIDYSEMDY------LIYE 162
             ::| ::.|::  ..|||.|  ...|:.||.:.:   ||..|| |||:   .||:      |:..
Mosquito   160 PVDVPQQSDEMFGMHGPIASVADSSKMPDIDDTA---EDIWNNFEDDV---SMDHTSALIPLMES 218

  Fly   163 SDTEVDAKQELKSDSENPKKRRNRRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCE 227
            |...|....|  :||:.|.:...      :.....|     .::|...:|     .:|..::.|.
Mosquito   219 SSYSVSVAPE--TDSQRPFREVY------NGEALVC-----LVQDGFLYI-----QKGKGQWHCR 265

  Fly   228 FCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTS 292
             .||  |..|.::|                 ....|..|   :...||:.     ||..|:.|..
Mosquito   266 -VED--CAAAIIRR-----------------AESEDLET---NNILHTHN-----KEVENSATDL 302

  Fly   293 YI---LKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYRSNAHRRN 335
            .|   |||         |....:.|:||        ||..|..:.|
Mosquito   303 QIWQLLKN---------ASPNGMSDELF--------HYVKNVKKGN 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	21/83 (25%)
		C2H2 Zn finger	198..218	CDD:275368	3/19 (16%)
		COG5048	222..>276	CDD:227381	9/53 (17%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	1/23 (4%)
		C2H2 Zn finger	254..274	CDD:275368	2/19 (11%)
		zf-H2C2_2	269..291	CDD:290200	5/21 (24%)
		C2H2 Zn finger	282..302	CDD:275368	8/22 (36%)
		zf-H2C2_2	295..319	CDD:290200	7/23 (30%)
		C2H2 Zn finger	310..328	CDD:275368	4/17 (24%)
AgaP_AGAP004541	XP_001688465.2	zf-AD	44..117	CDD:214871	23/86 (27%)
		FLYWCH	323..382	CDD:282369	3/9 (33%)
		FLYWCH	463..522	CDD:282369
		FLYWCH	546..605	CDD:282369
		FLYWCH	691..752	CDD:282369
		FLYWCH	796..856	CDD:282369
		FLYWCH	943..1005	CDD:282369
		FLYWCH	1058..1118	CDD:282369
		FLYWCH	1267..1332	CDD:282369
		FLYWCH	1394..1449	CDD:282369
		FLYWCH	1608..1664	CDD:282369
		FLYWCH	2126..2176	CDD:282369
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24388
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100