DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and znf280d

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_005166581.1	Gene:	znf280d / 556610	ZFINID:	ZDB-GENE-030131-2260	Length:	879	Species:	Danio rerio

Alignment Length:	186	Identity:	49/186 - (26%)
Similarity:	81/186 - (43%)	Gaps:	34/186 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 KSDSE---NPKKRRNRRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFG---------C 226
            |||.:   .||.:        ||.||.|..|...:|:.|.|:.|.|.|..:::..         |
Zfish   333 KSDGDPSLMPKIK--------SNTTFKCNSCLKMLKNNIRFMNHMKHHLELEKQNSESWESHTTC 389

  Fly   227 EFCEDRFCTPAELKRHIRKHTGEKPFK----CRHCSRSFSDYSTRLKHERTH--TNERPFVCKEC 285
            :.|..::.||.:|:.||  .:...||:    |:.|..:|......|:|.|.:  ..|.|:.|:.|
Zfish   390 QHCYRQYSTPFQLQCHI--ESAHSPFESSTNCKICELAFETEQVLLEHMRDNHKPGEMPYGCQVC 452

  Fly   286 NNAFTTSYI--LKNHM-LVHTGEKAFRCDLCDKLFSRYTHLTTHYRSNAHRRNMQK 338
            |  :.:|:.  :.||. .||...|...|..|.|:. |..|:...:.....::.:|:
Zfish   453 N--YRSSFFCDVDNHFRTVHENTKDLLCPFCLKVL-RSGHMYMQHYMRHQKKGIQR 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	7/19 (37%)
		COG5048	222..>276	CDD:227381	15/68 (22%)
		C2H2 Zn finger	226..246	CDD:275368	7/19 (37%)
		zf-H2C2_2	238..262	CDD:290200	7/27 (26%)
		C2H2 Zn finger	254..274	CDD:275368	6/19 (32%)
		zf-H2C2_2	269..291	CDD:290200	7/23 (30%)
		C2H2 Zn finger	282..302	CDD:275368	6/22 (27%)
		zf-H2C2_2	295..319	CDD:290200	8/24 (33%)
		C2H2 Zn finger	310..328	CDD:275368	5/17 (29%)
znf280d	XP_005166581.1	C2H2 Zn finger	352..386	CDD:275371	8/33 (24%)
		C2H2 Zn finger	389..410	CDD:275368	7/22 (32%)
		C2H2 Zn finger	419..440	CDD:275368	6/20 (30%)
		C2H2 Zn finger	449..468	CDD:275368	6/20 (30%)
		DUF2890	740..>821	CDD:287991
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910