DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and znf84

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001016873.1	Gene:	znf84 / 549627	XenbaseID:	XB-GENE-5721064	Length:	385	Species:	Xenopus tropicalis

Alignment Length:	158	Identity:	57/158 - (36%)
Similarity:	67/158 - (42%)	Gaps:	28/158 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 CEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFS 262
            |.|||.....:...:.|.|.|.|.|.|.|..|...|....:|:.|.|.|||||||.|..|.:.||
Frog    51 CTECGKSFSVKYHLVKHFKTHTGAKPFMCMECGKTFSEKDQLQAHSRVHTGEKPFSCVECGKRFS 115

  Fly   263 DYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLF---SRY---- 320
            .......|..|||.|:||.|.||...|.....|.:|.|:|.|||.|.|.:|.|.|   |.|
Frog   116 SKGGLQYHHTTHTGEKPFTCTECGKCFPNVSGLNSHRLIHAGEKPFPCTVCGKSFISRSDYIGHS 180

  Fly   321 ---------------------THLTTHY 327
                                 |:||.||
Frog   181 RIHTGEKPFACTECGKRFCLKTNLTRHY 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	6/19 (32%)
		COG5048	222..>276	CDD:227381	22/53 (42%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	12/23 (52%)
		C2H2 Zn finger	254..274	CDD:275368	5/19 (26%)
		zf-H2C2_2	269..291	CDD:290200	11/21 (52%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		zf-H2C2_2	295..319	CDD:290200	12/26 (46%)
		C2H2 Zn finger	310..328	CDD:275368	11/46 (24%)
znf84	NP_001016873.1	C2H2 Zn finger	23..43	CDD:275368
		COG5048	<31..208	CDD:227381	55/156 (35%)
		zf-H2C2_2	35..59	CDD:290200	4/7 (57%)
		C2H2 Zn finger	51..71	CDD:275368	6/19 (32%)
		zf-H2C2_2	63..87	CDD:290200	8/23 (35%)
		C2H2 Zn finger	79..99	CDD:275368	6/19 (32%)
		zf-H2C2_2	92..116	CDD:290200	13/23 (57%)
		C2H2 Zn finger	107..127	CDD:275368	5/19 (26%)
		zf-H2C2_2	120..142	CDD:290200	10/21 (48%)
		C2H2 Zn finger	135..155	CDD:275368	7/19 (37%)
		zf-H2C2_2	148..170	CDD:290200	11/21 (52%)
		C2H2 Zn finger	163..183	CDD:275368	6/19 (32%)
		zf-H2C2_2	179..198	CDD:290200	0/18 (0%)
		C2H2 Zn finger	191..211	CDD:275368	5/18 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910