DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and LOC549508

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_031759247.1	Gene:	LOC549508 / 549508	-ID:	-	Length:	1464	Species:	Xenopus tropicalis

Alignment Length:	414	Identity:	103/414 - (24%)
Similarity:	155/414 - (37%)	Gaps:	92/414 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTCGKRTNAERSLNI-------------------FEKRNQTTLEHIKLLTGA---VLKNCS--- 45
            ||.|||....:|.|.:                   |:.:.|.|| |:::.||.   |...|.
Frog   941 CRECGKSFRVKRQLTLHLQTHTGEKPFDCSECGKSFKVKRQLTL-HLQIHTGEKPFVCTECGKSF 1004

  Fly    46 TLPNRLCASCQT--------CLQQAISFR-ERCLEVQRELLHSQDDEDFLRICQESPKSVLEQEE 101
            .:..:|....||        |.:...||| :|.|...:::..|....:.|.|.::...|.:...:
Frog  1005 RVQGKLTVHLQTHTGEKPFVCTECGKSFRSKRSLSSHQKVHKSSTATENLHIGKKQCFSAMSIPD 1069

  Fly   102 LELDLAEI-----------------SIEVERLDDLNEGPIQ----SSGF-KVEDILNESKINEDE 144
            .:.:|..:                 |:.:.:.....|.|..    ...| |...::...:::..|
Frog  1070 SQKELPSVIKHFKCPECGRRYSSKGSLIIHQRVHTGEKPFMCTECGKNFSKKYGLVVHQRVHTGE 1134

  Fly   145 PN---NEDDIDYSEMDYLIYESDTEVDAKQEL-----KSDSENPK----KR-------------- 183
            ..   .|....::|.:|||.........|...     |..||..|    :|
Frog  1135 KPFMCTECGKRFTEKNYLIIHQTLHTGEKPFTCTECGKGFSEKRKCVIHQRVHTGEKPFTCTECG 1199

  Fly   184 ---------RNRRNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAEL 239
                     ::.:......:.:.|.|||.........:.|.:.|.|:|.|.|..|...|....:|
Frog  1200 KCFSVKSGLKSHQRIHTGEKPYTCTECGKSFTLNSHLVRHQRIHTGIKPFACTECGKSFSAHHKL 1264

  Fly   240 KRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTG 304
            ..|.|.|||||||.|..|.:|||.:.....|:|.||.|:||.|.||..:|:..::|..|..||||
Frog  1265 SLHKRVHTGEKPFTCTECGKSFSAHDKLSLHKRVHTGEKPFTCTECGKSFSAHHMLSLHKRVHTG 1329

  Fly   305 EKAFRCDLCDKLFSRYTHLTTHYR 328
            ||.|.|..|.|.|.:.|||..|.|
Frog  1330 EKPFTCTECGKSFRQQTHLEIHQR 1353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	25/104 (24%)
		C2H2 Zn finger	198..218	CDD:275368	5/19 (26%)
		COG5048	222..>276	CDD:227381	23/53 (43%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	13/23 (57%)
		C2H2 Zn finger	254..274	CDD:275368	7/19 (37%)
		zf-H2C2_2	269..291	CDD:290200	11/21 (52%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	13/23 (57%)
		C2H2 Zn finger	310..328	CDD:275368	8/17 (47%)
LOC549508	XP_031759247.1	C2H2 Zn finger	183..203	CDD:275368
		C2H2 Zn finger	210..230	CDD:275368
		C2H2 Zn finger	238..258	CDD:275368
		C2H2 Zn finger	298..318	CDD:275368
		C2H2 Zn finger	326..346	CDD:275368
		C2H2 Zn finger	354..374	CDD:275368
		C2H2 Zn finger	382..402	CDD:275368
		C2H2 Zn finger	410..430	CDD:275368
		COG5048	<429..614	CDD:227381
		C2H2 Zn finger	438..458	CDD:275368
		C2H2 Zn finger	465..485	CDD:275368
		C2H2 Zn finger	493..513	CDD:275368
		C2H2 Zn finger	521..541	CDD:275368
		COG5048	545..949	CDD:227381	5/7 (71%)
		C2H2 Zn finger	549..569	CDD:275368
		C2H2 Zn finger	577..597	CDD:275368
		C2H2 Zn finger	605..625	CDD:275368
		C2H2 Zn finger	633..653	CDD:275368
		C2H2 Zn finger	661..681	CDD:275368
		C2H2 Zn finger	689..709	CDD:275368
		C2H2 Zn finger	717..737	CDD:275368
		C2H2 Zn finger	745..765	CDD:275368
		C2H2 Zn finger	773..793	CDD:275368
		C2H2 Zn finger	801..821	CDD:275368
		C2H2 Zn finger	829..849	CDD:275368
		C2H2 Zn finger	857..877	CDD:275368
		C2H2 Zn finger	885..905	CDD:275368
		C2H2 Zn finger	913..933	CDD:275368
		C2H2 Zn finger	941..961	CDD:275368	7/19 (37%)
		COG5048	965..1346	CDD:227381	91/381 (24%)
		C2H2 Zn finger	969..989	CDD:275368	5/20 (25%)
		C2H2 Zn finger	997..1017	CDD:275368	3/19 (16%)
		C2H2 Zn finger	1025..1045	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1083..1103	CDD:275368	1/19 (5%)
		C2H2 Zn finger	1111..1131	CDD:275368	2/19 (11%)
		C2H2 Zn finger	1139..1159	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1167..1187	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1195..1215	CDD:275368	0/19 (0%)
		C2H2 Zn finger	1223..1243	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1251..1271	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1279..1299	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1307..1327	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1335..1355	CDD:275368	9/19 (47%)
		C2H2 Zn finger	1363..1383	CDD:275368
		zf-H2C2_2	1375..1399	CDD:404364
		C2H2 Zn finger	1391..1411	CDD:275368
		zf-H2C2_2	1403..1427	CDD:404364
		C2H2 Zn finger	1419..1439	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910