DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and CG1792

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	391	Identity:	131/391 - (33%)
Similarity:	174/391 - (44%)	Gaps:	90/391 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEGKVCRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKN--CSTLPNRLCASCQTCLQQAI 63
            |..:.|||||.........|:||:.|...|..|::|||..|..  .:.||..:|:.|:..||.||
  Fly     1 MPNRNCRTCGLFIFCSTPSNLFEEPNSVMLHQIEVLTGLFLLGGPGNELPPFICSPCELDLQTAI 65

  Fly    64 SFRERCLEVQRELLHSQDDEDFLRICQESP--------KSVLEQEELELDLAEISIEVERLDDLN 120
            :||||.:..|:.|             ||||        :|.....|.|:..||...|:|.:|.|.
  Fly    66 AFRERVIRTQKTL-------------QESPNLGNAELIESFAVGVEKEIQYAEEVTEIEVIDLLP 117

  Fly   121 EGPIQSSGFKVEDILNESKINEDEPNNEDDIDYSEMDYLIYESDTEVDAK---QELK-------- 174
            |          |.:|.|:    :||            |.|.|.:.:...|   ||.|
  Fly   118 E----------EHLLEET----EEP------------YEICEQNEQPQVKVPAQEKKLRRSTKTT 156

  Fly   175 -----------------------SDSENPKKRRNRRNPRDSNRTFFCEECGNHIKDRISFILHCK 216
                                   ::.|....:|.||     .|...||:||.|.....:|.||..
  Fly   157 PTVFTSVKFADNSQATRTQWSRLTEDEVVALKRERR-----KRDCICEQCGRHFTCPSNFKLHLL 216

  Fly   217 RHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFSDYSTRLKHER-THTNERPF 280
            ||.|||.|.|:.|..:|.|...|:||...|.|...|:||:|..::|:.|.|::||| .|||.:||
  Fly   217 RHTGVKSFACDQCSQQFYTATLLRRHQELHAGNALFQCRYCEATYSNASGRIQHERMRHTNVKPF 281

  Fly   281 VCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHYRSNAHRRNMQKADTIFDK 345
            .|||||.:|..|..|:.|||.|||.:||.||.|...|.|.:|||:||||..| .:...|....|.
  Fly   282 TCKECNKSFAMSGKLRTHMLSHTGVRAFHCDSCQVSFVRRSHLTSHYRSKGH-AHTSSAQAALDN 345

  Fly   346 P 346
            |
  Fly   346 P 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	28/73 (38%)
		C2H2 Zn finger	198..218	CDD:275368	8/19 (42%)
		COG5048	222..>276	CDD:227381	22/54 (41%)
		C2H2 Zn finger	226..246	CDD:275368	7/19 (37%)
		zf-H2C2_2	238..262	CDD:290200	9/23 (39%)
		C2H2 Zn finger	254..274	CDD:275368	9/20 (45%)
		zf-H2C2_2	269..291	CDD:290200	14/22 (64%)
		C2H2 Zn finger	282..302	CDD:275368	11/19 (58%)
		zf-H2C2_2	295..319	CDD:290200	13/23 (57%)
		C2H2 Zn finger	310..328	CDD:275368	9/17 (53%)
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871	29/86 (34%)
		C2H2 Zn finger	198..218	CDD:275368	8/19 (42%)
		C2H2 Zn finger	226..243	CDD:275368	6/16 (38%)
		C2H2 Zn finger	254..275	CDD:275368	9/20 (45%)
		zf-C2H2	281..303	CDD:278523	12/21 (57%)
		C2H2 Zn finger	283..303	CDD:275368	11/19 (58%)
		zf-H2C2_2	296..320	CDD:290200	13/23 (57%)
		C2H2 Zn finger	311..329	CDD:275368	9/17 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447757
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	1	1.100	-	-	P	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.890