DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and CG17801

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_650660.2	Gene:	CG17801 / 42144	FlyBaseID:	FBgn0038550	Length:	381	Species:	Drosophila melanogaster

Alignment Length:	355	Identity:	100/355 - (28%)
Similarity:	154/355 - (43%)	Gaps:	48/355 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 LEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRERCLEVQRELLHSQD---DEDF----LR 87
            |..||.|||..|:.....|..:|.||...|..:|..::|...|..|....::   |||.    ..
  Fly    31 LAKIKDLTGIWLEQNERQPRHICPSCLNDLNTSIKLKKRIQRVHNEATLRRESGLDEDLESTVSD 95

  Fly    88 ICQESPKSVLEQEE----------LELDLAEISIEVERLDDLNE--GPIQSSG---FKVEDILNE 137
            |..|...|.||.||          .:.:.::|.:.:...|..||  .|..|..   ||.::.|.|
  Fly    96 IEPEGDSSDLESEESYDSENYPFDKKAEESDIDLNLAHEDRRNEPHNPYDSETPLIFKHKNPLIE 160

  Fly   138 --SKINEDEPNNEDDIDYSEMDYLIYESDTEV--------------DAKQELKSDSENPKKRRNR 186
              |..||:.||..|.....:.:::...:|..:              .|.:::.:::..|.||..|
  Fly   161 TPSFANENLPNKVDAKSPKKGNFIQIGTDLRLLTTYPSIKVVKPLALAPEDVAAENVPPAKRTAR 225

  Fly   187 RNPRDSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIR-KHTGEK 250
            :     .::..|.:||...|...:...|..||.|.|.|.|.||:.||.|....:.|.| :|.||:
  Fly   226 K-----MQSLVCPKCGRVFKTPYNLKTHMVRHTGEKNFPCTFCDKRFVTKYLARLHERVRHMGEQ 285

  Fly   251 PFKCRHCSRSFSDYSTRLKHER-THTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCD 314
            ||:|..||.:|...:.:..||| .|..:..:.|.:|...|.|...|..|..:|:|.|.|.|.:|.
  Fly   286 PFECNFCSATFFTSTAKSSHERIRHIRDLRYQCDQCTKRFNTKTCLNKHKFLHSGLKPFDCVICQ 350

  Fly   315 KLFSRYTHLTTHYRSNAHRRNMQKADTIFD 344
            ..|:|...|.:|:.|.||::   :|..|.:
  Fly   351 INFARKATLRSHFDSVAHQK---RASAILE 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	16/46 (35%)
		C2H2 Zn finger	198..218	CDD:275368	5/19 (26%)
		COG5048	222..>276	CDD:227381	23/55 (42%)
		C2H2 Zn finger	226..246	CDD:275368	8/20 (40%)
		zf-H2C2_2	238..262	CDD:290200	10/24 (42%)
		C2H2 Zn finger	254..274	CDD:275368	7/20 (35%)
		zf-H2C2_2	269..291	CDD:290200	7/22 (32%)
		C2H2 Zn finger	282..302	CDD:275368	6/19 (32%)
		zf-H2C2_2	295..319	CDD:290200	9/23 (39%)
		C2H2 Zn finger	310..328	CDD:275368	6/17 (35%)
CG17801	NP_650660.2	zf-AD	9..74	CDD:285071	14/42 (33%)
		zf-C2H2	231..252	CDD:278523	5/20 (25%)
		C2H2 Zn finger	232..252	CDD:275368	5/19 (26%)
		zf-H2C2_2	244..269	CDD:290200	11/24 (46%)
		C2H2 Zn finger	260..281	CDD:275368	8/20 (40%)
		C2H2 Zn finger	289..308	CDD:275368	6/18 (33%)
		C2H2 Zn finger	318..338	CDD:275368	6/19 (32%)
		C2H2 Zn finger	346..362	CDD:275368	5/15 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	1	1.100	-	-	P	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.960