DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ranshi and CG14710

DIOPT Version :9

Sequence 1:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_650092.4	Gene:	CG14710 / 41393	FlyBaseID:	FBgn0037920	Length:	415	Species:	Drosophila melanogaster

Alignment Length:	409	Identity:	117/409 - (28%)
Similarity:	180/409 - (44%)	Gaps:	76/409 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTCGKRTNAERSLNIFEKRNQTTL-EHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRERC 69
            ||.|.......:.:.:|..:.::.| :.::|.....::....||.:.|.||...:|...:||:.|
  Fly    10 CRICLGDFEESQMICLFGDKGESDLRKKLELCCRIRVRQSPQLPEKACNSCCEFVQMWFNFRQMC 74

  Fly    70 LEVQ----------RELLHSQDDEDFLRICQES--PKSVLEQEELELDLAEISIEVERLDDLNEG 122
            |..|          .|.|....|.:::....|:  .|...|.:|.| ::..|....|:.:|.::.
  Fly    75 LNSQVYWETSSSERPEALAQASDAEYMLYLYENLHLKLGTENQEKE-EITAIEEGDEQQEDQSQE 138

  Fly   123 PIQSSGFKVEDILNESKINEDEPNNE--DDIDYSEMDYLIYESDTE--VDAKQEL---------- 173
            .:..:||    |:|||...::|||.|  :.|..|.||..:.:...|  :|.|.||
  Fly   139 VLDFNGF----IINESIEEDEEPNTESPEQILISHMDSYVDDQQMEELIDDKGELVEELSNANTF 199

  Fly   174 ---------------------------------KSDSE--------NPKKRRNRRNPRDSNRTFF 197
                                             |.|:|        |.|:|.|:...::..: |.
  Fly   200 YEVEYGDEELLMSSAPSPHPSFKMDKQKPGRPRKPDAELKFKRKDINAKERGNQPKCKEEEK-FM 263

  Fly   198 CEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCRHCSRSFS 262
            |..|||....:..|..|...|...|...||.|...|....||:.|||:|||::|:||.:|.|.|.
  Fly   264 CILCGNVFYKKSVFTAHMMTHSEYKPHQCEICNKSFRQMGELRAHIRRHTGDRPYKCMYCDRHFY 328

  Fly   263 DYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRYTHLTTHY 327
            |.|.|::|||.|||.||:.|:||...||.:.|||||:|.|:.:|.:.|.:|.|.|:....|..|.
  Fly   329 DRSERVRHERVHTNTRPYACQECGKTFTHTAILKNHILSHSAQKNYNCGICCKSFTLLHQLKAHL 393

  Fly   328 RSNAHRRNMQKADTIFDKP 346
            ::..||..|::  ||...|
  Fly   394 QTLTHRNKMEQ--TIPSSP 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	18/81 (22%)
		C2H2 Zn finger	198..218	CDD:275368	6/19 (32%)
		COG5048	222..>276	CDD:227381	26/53 (49%)
		C2H2 Zn finger	226..246	CDD:275368	9/19 (47%)
		zf-H2C2_2	238..262	CDD:290200	13/23 (57%)
		C2H2 Zn finger	254..274	CDD:275368	10/19 (53%)
		zf-H2C2_2	269..291	CDD:290200	12/21 (57%)
		C2H2 Zn finger	282..302	CDD:275368	11/19 (58%)
		zf-H2C2_2	295..319	CDD:290200	11/23 (48%)
		C2H2 Zn finger	310..328	CDD:275368	6/17 (35%)
CG14710	NP_650092.4	zf-AD	9..83	CDD:285071	17/72 (24%)
		COG5048	<261..395	CDD:227381	57/134 (43%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		zf-C2H2	290..312	CDD:278523	9/21 (43%)
		C2H2 Zn finger	292..312	CDD:275368	9/19 (47%)
		zf-H2C2_2	304..327	CDD:290200	13/22 (59%)
		C2H2 Zn finger	320..340	CDD:275368	10/19 (53%)
		zf-H2C2_2	335..357	CDD:290200	12/21 (57%)
		C2H2 Zn finger	348..368	CDD:275368	11/19 (58%)
		C2H2 Zn finger	376..395	CDD:275368	6/18 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960